WormBase Tree Display for Gene: WBGene00018064
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| WBGene00018064 | SMap | S_parent | Sequence | F35F11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cdc-73 | Person_evidence | WBPerson634 | |||||
| Sequence_name | F35F11.1 | ||||||||
| Molecular_name | F35F11.1 | ||||||||
| F35F11.1.1 | |||||||||
| CE48035 | |||||||||
| Other_name | CELE_F35F11.1 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | cdc-73 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:59 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 10 Mar 2014 11:27:18 | WBPerson2970 | Name_change | CGC_name | cdc-73 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cdc | ||||||||
| Allele (134) | |||||||||
| Strain | WBStrain00002926 | ||||||||
| WBStrain00051276 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00095606 | ||||||||
| 00095607 | |||||||||
| 00095608 | |||||||||
| 00095609 | |||||||||
| 00095610 | |||||||||
| 00095611 | |||||||||
| 00123309 | |||||||||
| 00123310 | |||||||||
| Ortholog (50) | |||||||||
| Structured_description | Concise_description | cdc-73 encodes the C. elegans ortholog of mammalian and Saccharomyces cerevisiae CDC73/Parafibromin that is a member of the PAF1 (Polymerase-Associated Factor 1) complex; by homology CDC-73 is predicted to function in the regulation of transcription. | Curator_confirmed | WBPerson1843 | |||||
| Date_last_updated | 23 Mar 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in positive regulation of transcription elongation by RNA polymerase II and recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex. Predicted to be located in nucleus. Predicted to be part of Cdc73/Paf1 complex. Human ortholog(s) of this gene implicated in carcinoma (multiple); colorectal cancer; and hyperparathyroidism. Is an ortholog of human CDC73 (cell division cycle 73). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0050866 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16783) | ||||
| DOID:13543 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16783) | ||||||
| DOID:9256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16783) | ||||||
| DOID:2876 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16783) | ||||||
| DOID:3910 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16783) | ||||||
| DOID:1540 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16783) | ||||||
| DOID:5520 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16783) | ||||||
| Molecular_info | Corresponding_CDS | F35F11.1 | |||||||
| Corresponding_CDS_history | F35F11.1:wp129 | ||||||||
| F35F11.1:wp234 | |||||||||
| Corresponding_transcript | F35F11.1.1 | ||||||||
| Other_sequence (15) | |||||||||
| Associated_feature | WBsf645899 | ||||||||
| WBsf996161 | |||||||||
| WBsf996162 | |||||||||
| WBsf996163 | |||||||||
| WBsf996164 | |||||||||
| WBsf996165 | |||||||||
| WBsf1017182 | |||||||||
| WBsf228148 | |||||||||
| WBsf228149 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00110693 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00061522 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00110692 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00046381 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00106605 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00033317 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00106680 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00110697 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr5954 | ||||||||
| Expr1013621 | |||||||||
| Expr1037783 | |||||||||
| Expr1150260 | |||||||||
| Expr2009791 | |||||||||
| Expr2028031 | |||||||||
| Drives_construct | WBCnstr00003438 | ||||||||
| WBCnstr00026805 | |||||||||
| Construct_product | WBCnstr00026805 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (92) | |||||||||
| Interaction (21) | |||||||||
| Map_info | Map | IV | Position | -0.972862 | |||||
| Positive | Positive_clone | F35F11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00045133 | |||||||||
| WBPaper00048493 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059048 | |||||||||
| WBPaper00062625 | |||||||||
| WBPaper00063228 | |||||||||
| WBPaper00063960 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
