WBGene00018339 | SMap | S_parent | Sequence | F42A10 |
| Identity | Version | 2 |
| | Name | CGC_name | abcf-3 | Paper_evidence | WBPaper00028961 |
| | | Sequence_name | F42A10.1 |
| | | Molecular_name | F42A10.1 |
| | | | F42A10.1.1 |
| | | | CE01292 |
| | | | F42A10.1.2 |
| | | Other_name | CELE_F42A10.1 | Accession_evidence | NDB | BX284603 |
| | | Public_name | abcf-3 |
| | DB_info | Database | AceView | gene | 3H265 |
| | | | WormQTL | gene | WBGene00018339 |
| | | | WormFlux | gene | WBGene00018339 |
| | | | NDB | locus_tag | CELE_F42A10.1 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00018339|UniProtKB=Q20306 |
| | | | | family | PTHR19211 |
| | | | NCBI | gene | 175873 |
| | | | RefSeq | protein | NM_065938.8 |
| | | | TREEFAM | TREEFAM_ID | TF105209 |
| | | | TrEMBL | UniProtAcc | Q20306 |
| | | | UniProt_GCRP | UniProtAcc | Q20306 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 28 May 2004 13:31:00 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 |
| | | | 2 | 21 Jun 2007 14:37:04 | WBPerson2970 | Name_change | CGC_name | abcf-3 |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | abcf |
| | Allele (43) |
| | Strain | WBStrain00036919 |
| | RNASeq_FPKM (74) |
| | GO_annotation | 00067765 |
| | | 00067766 |
| | | 00067767 |
| | | 00067768 |
| | | 00067769 |
| | | 00067770 |
| | | 00067771 |
| | | 00067772 |
| | | 00123486 |
| | | 00123487 |
| | Ortholog (38) |
| | Paralog | WBGene00006512 | Caenorhabditis elegans | From_analysis | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00012097 | Caenorhabditis elegans | From_analysis | Panther |
| | | | | | WormBase-Compara |
| | Structured_description | Concise_description | abcf-3 encodes a protein with sequence similarity to AAA ATPases that is the C. elegans ortholog of the S. cerevisiae ribosome-association protein Gcn20p; ABCF-3, along with GCN-1, is required for maintaining the steady-state levels of phosphorylated eIF2alpha, and thus for the translational control of a number of mRNAs; ABCF-3 activity is required, in parallel to, or downstream of, the canonical apoptotic pathway, for apoptotic cell death of most somatic cells and germ cells in response to ionizing radiation; in addition, ABCF-3 is required for normal growth rates, and spatial organization of germ cells in the gonad; as in S. cerevisiae, ABCF-3 physically interacts with GCN-1, the C. elegans ortholog of budding yeast Gcn1p, and GCN-1 and ABCF-3 are each required for the other's stability; an abcf-3::gfp promoter fusion is expressed in most cells, including germ cells, throughout development. | Paper_evidence | WBPaper00045601 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | Date_last_updated | 15 Aug 2014 00:00:00 |
| | | Automated_description | Predicted to enable ATP binding activity. Involved in positive regulation of peptidyl-serine phosphorylation; regulation of apoptotic process; and regulation of translation. Predicted to be located in cytosolic ribosome. Expressed in several structures, including body wall musculature; head neurons; hermaphrodite gonad; intestinal cell; and pharyngeal neurons. Is an ortholog of human ABCF3 (ATP binding cassette subfamily F member 3). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | F42A10.1 |
| | Corresponding_transcript | F42A10.1.1 |
| | | F42A10.1.2 |
| | Other_sequence (124) |
| | Associated_feature | WBsf645248 |
| | | WBsf645249 |
| | | WBsf658487 |
| | | WBsf225066 |
| | | WBsf225067 |
| Experimental_info | RNAi_result | WBRNAi00047060 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00005924 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00014789 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00032115 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00047059 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00005121 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00047054 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Expr11921 |
| | | Expr11924 |
| | | Expr1016169 |
| | | Expr1037895 |
| | | Expr1150917 |
| | | Expr2009076 |
| | | Expr2027312 |
| | Drives_construct | WBCnstr00019542 |
| | | WBCnstr00026600 |
| | Construct_product | WBCnstr00019543 |
| | | WBCnstr00026600 |
| | Antibody | WBAntibody00002555 |
| | Microarray_results (21) |
| | Expression_cluster | WBPaper00031040:TGF-beta_adult_downregulated |
| | | WBPaper00032031:DConiospora_upregulated_cDNA_24h |
| | | WBPaper00032528:L3_enriched |
| | | WBPaper00033065:cyc-1(RNAi)_upregulated |
| | | WBPaper00037047:aging_accelerated_insoluble_protein |
| | | WBPaper00037047:insoluble_protein |
| | | WBPaper00037950:AVA-neuron_L1-larva_expressed |
| | | WBPaper00037950:BAG-neuron_blastula-embryo_expressed |
| | | WBPaper00037950:bodywall-muscle_L2-larva_expressed |
| | | WBPaper00037950:coelomocytes_L1-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L1-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed |
| | | WBPaper00037950:excretory-cell_L2-larva_expressed |
| | | WBPaper00037950:hypodermis_L3-L4-larva_expressed |
| | | WBPaper00037950:intestine_L1-larva_expressed |
| | | WBPaper00037950:intestine_L2-larva_expressed |
| | | WBPaper00038213:E.coli(LF82)_24h_upregulated |
| | | WBPaper00040209:B.thuringiensis_upregulated_MY15 |
| | | WBPaper00040221:DAF-12_target_ALF4 |
| | | WBPaper00042477:rsr-2(RNAi)_downregulated_RNAseq |
| | | WBPaper00044426:rotenone_24h_downregulated |
| | | WBPaper00044656:tatn-1(qd182)_downregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00044746:aging_downregulated_HeatShock |
| | | WBPaper00045314:S.aureus-induced_hlh-30(tm1978) |
| | | WBPaper00045314:S.aureus-induced_N2 |
| | | WBPaper00045729:gld-4(RNAi)_downregulated |
| | | WBPaper00045774:clk-1_downregulated |
| | | WBPaper00046303:P.aeruginosa_upregulated_protein |
| | | WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049545:jmjd-3.1(+)_upregulated |
| | | WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated |
| | | WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated |
| | | WBPaper00049954:BPS_downregulated |
| | | WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult |
| | | WBPaper00050488:20C_vs_25C_regulated_N2_adult |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050698:DEP-1_interacting |
| | | WBPaper00050990:arcade_intestinal-valve_expressed |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00051039:germline_enriched |
| | | WBPaper00051245:epidermis_cytoplasm_expressed |
| | | WBPaper00051245:intestine_cytoplasm_expressed |
| | | WBPaper00053184:sma-2(rax5)_downregulated |
| | | WBPaper00053184:sma-4(rax3)_downregulated |
| | | WBPaper00053321:embryo-to-L1_upregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq |
| | | WBPaper00053388:dauer_regulated_Cluster2 |
| | | WBPaper00053599:oocyte_vs_mitosis_upregulated |
| | | WBPaper00053615:SMO-1_target |
| | | WBPaper00053810:daf-2(e1370)_downregulated |
| | | WBPaper00053810:isp-1(qm150)_downregulated |
| | | WBPaper00053810:nuo-6(qm200)_downregulated |
| | | WBPaper00053814:25C_downregulated_OP50 |
| | | WBPaper00053814:25C_downregulated_PY79 |
| | | WBPaper00055354:Rapamycin-Metformin_upregulated |
| | | WBPaper00055354:Rapamycin-Rifampicin_upregulated |
| | | WBPaper00055648:germline_expressed |
| | | WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047) |
| | | WBPaper00056443:sek-1(km4)_downregulated |
| | | WBPaper00056997:NMAD-1_interacting |
| | | WBPaper00057288:Cold_downregulated_protein |
| | | WBPaper00057288:Cold_downregulated_transcript |
| | | WBPaper00057288:iff-1(RNAi)_downregulated_transcript |
| | | WBPaper00058598:sin-3(tm1276)_downregulated |
| | | WBPaper00058691:cfp-1(tm6369)_downregulated |
| | | WBPaper00059254:CSR-1_interacting |
| | | WBPaper00059605:MUT-16_interacting |
| | | WBPaper00061203:sin-3(tm1276)_upregulated |
| | | WBPaper00061203:spr-1(ok2144)_upregulated |
| | | WBPaper00061341:28C_24h_downregulated |
| | | WBPaper00061478:SUMO-conjugated_protein |
| | | WBPaper00061527:tars-1-AFFX-r2-3026-5_at |
| | | WBPaper00062123:DEPS-1_interacting |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062554:MAGU-2_interacting |
| | | WBPaper00062669:extracellular-vesicle_protein |
| | | WBPaper00064005:starvation_upregulated_N2_mRNA |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00065373:sek-1(km4)_downregulated_cisplatin |
| | | WBPaper00065975:P-body_vs_oocyte_depleted |
| | | WBPaper00065975:P-body_vs_WholeAnimal_depleted |
| | | WBPaper00065993:glp-1(e2141)_downregulated |
| | | WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14 |
| | | cgc4489_group_3 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00030839:Embryo_Pan_Neuronal |
| | | WBPaper00030985:Photorhabdus_luminescens_upregulated |
| | | WBPaper00032165:differentially_expressed_with_age_medoid_6 |
| | | WBPaper00035479:daf-16(RNAi)_upregulated |
| | | WBPaper00036286:Pattern_H |
| | | WBPaper00037695:DD_3-day |
| | | WBPaper00037695:WC_5-day |
| | | WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2down |
| | | WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2 |
| | | WBPaper00041606:CE_B.thuringiensis-DB27_regulated |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | WBPaper00045263:isp-1(qm150)_downregulated |
| | | WBPaper00045263:nuo-6(qm200)_downregulated |
| | | WBPaper00045960:L1-L4-lethargus_downregulated |
| | | WBPaper00045960:L4-lethargus_downregulated |
| | | WBPaper00053236:Starvation_regulated_GR1307 |
| | | WBPaper00053236:Starvation_regulated_N2 |
| | | [cgc5767]:expression_class_E |
| | | [cgc5767]:expression_class_E_pi(23_min) |
| | | [cgc5767]:expression_class_M |
| | | [cgc5767]:expression_class_ME |
| | Interaction (118) |
| Map_info | Map | III | Position | -1.41034 | Error | 0.000332 |
| | Positive | Positive_clone | F42A10 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Pseudo_map_position |
| Reference | WBPaper00029084 |
| | WBPaper00033469 |
| | WBPaper00038491 |
| | WBPaper00039498 |
| | WBPaper00042646 |
| | WBPaper00045601 |
| | WBPaper00055090 |
| | WBPaper00061765 |
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene |