WormBase Tree Display for Gene: WBGene00018478
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WBGene00018478 | SMap | S_parent | Sequence | F45F2 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | otpl-5 | |||||||
Sequence_name | F45F2.5 | ||||||||
Molecular_name | F45F2.5 | ||||||||
F45F2.5.1 | |||||||||
CE45695 | |||||||||
Other_name | CELE_F45F2.5 | Accession_evidence | NDB | BX284605 | |||||
Public_name | otpl-5 | ||||||||
DB_info | Database | AceView | gene | 5J11 | |||||
WormQTL | gene | WBGene00018478 | |||||||
WormFlux | gene | WBGene00018478 | |||||||
NDB | locus_tag | CELE_F45F2.5 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00018478|UniProtKB=G4SFC1 | |||||||
family | PTHR21522 | ||||||||
NCBI | gene | 185806 | |||||||
RefSeq | protein | NM_072795.4 | |||||||
TREEFAM | TREEFAM_ID | TF313428 | |||||||
TrEMBL | UniProtAcc | G4SFC1 | |||||||
UniProt_GCRP | UniProtAcc | G4SFC1 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:31:00 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 07 Apr 2008 11:28:34 | WBPerson2970 | Name_change | CGC_name | otpl-5 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | otpl | ||||||||
Allele (41) | |||||||||
Strain | WBStrain00050996 | ||||||||
WBStrain00055623 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (13) | |||||||||
Ortholog (24) | |||||||||
Paralog | WBGene00010403 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00015035 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00017034 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
WormBase-Compara | |||||||||
WBGene00017449 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00018477 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00018479 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
WBGene00018480 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
Panther | |||||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | otpl-5 encodes an ortholog of otopetrins such as human OTOP1 (OMIM:607806), OTOP2 (OMIM:607827), and OTOP3 (OMIM:607828), along with other homologs in fish and insects (such as crustacean OTOPLb); otopetrins are predicted to have 12 transmembrane helices; by homology with OTOP1 and OTOPLb, OTPL-5 might regulate intracellular calcium fluxes during extracellular stimuli, promote extracellular calcium carbonate biomineralization, or both; OTPL-5's paralogs include OTPL-1 through OTPL-8; OTPL-5 has no function in mass RNAi assays. | Paper_evidence | WBPaper00031620 | |||||
WBPaper00031621 | |||||||||
WBPaper00031622 | |||||||||
WBPaper00031623 | |||||||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 04 Apr 2008 00:00:00 | ||||||||
Automated_description | Predicted to enable proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human OTOP1 (otopetrin 1); OTOP2 (otopetrin 2); and OTOP3 (otopetrin 3). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F45F2.5 | |||||||
Corresponding_CDS_history | F45F2.5:wp218 | ||||||||
Corresponding_transcript | F45F2.5.1 | ||||||||
Experimental_info | RNAi_result | WBRNAi00015037 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00047427 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00032318 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00103365 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr1012878 | ||||||||
Expr1151270 | |||||||||
Expr2014661 | |||||||||
Expr2032894 | |||||||||
Drives_construct | WBCnstr00026487 | ||||||||
Construct_product | WBCnstr00026487 | ||||||||
Microarray_results (16) | |||||||||
Expression_cluster (40) | |||||||||
Interaction (54) | |||||||||
Map_info | Map | V | Position | 1.4379 | Error | 0.000586 | |||
Positive | Positive_clone | F45F2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00031620 | ||||||||
WBPaper00031622 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00056048 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |