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WormBase Tree Display for Gene: WBGene00020586

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Name Class

WBGene00020586SMapS_parentSequenceT19F4
IdentityVersion2
NameCGC_namefrpr-18Person_evidenceWBPerson260
Sequence_nameT19F4.1
Molecular_nameT19F4.1a
T19F4.1a.1
CE28679
T19F4.1b
CE29349
T19F4.1c
CE52203
T19F4.1b.1
T19F4.1c.1
Other_nameCELE_T19F4.1Accession_evidenceNDBBX284605
Public_namefrpr-18
DB_infoDatabaseAceViewgene5H353
WormQTLgeneWBGene00020586
WormFluxgeneWBGene00020586
NDBlocus_tagCELE_T19F4.1
PanthergeneCAEEL|WormBase=WBGene00020586|UniProtKB=G5EEB1
familyPTHR47323
NCBIgene179076
RefSeqproteinNM_001356672.4
NM_072345.7
NM_001356671.3
SwissProtUniProtAccG5EEB1
TREEFAMTREEFAM_IDTF316702
UniProt_GCRPUniProtAccG5EEB1
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:03WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
220 Dec 2011 16:46:04WBPerson2970Name_changeCGC_namefrpr-18
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classfrpr
Allele (49)
StrainWBStrain00032724
RNASeq_FPKM (74)
GO_annotation (18)
Ortholog (29)
Paralog (187)
Structured_descriptionConcise_descriptionfrpr-18 encodes, by alternative splicing, two G-protein coupled receptors for the flp-2-encoded peptides SPREPIRFamide (FLP2-A) and LRGEPIRFamide (FLP2-B); T19F4.1B protein has an extension of 30 residues more than T19F4.1A in the intracellular C-terminal region; T19F4.1A/B are probably linked to the G(q) pathway.Paper_evidenceWBPaper00025071
WBPaper00044852
Person_evidenceWBPerson197
Curator_confirmedWBPerson324
WBPerson567
Date_last_updated10 Feb 2016 00:00:00
Automated_descriptionEnables G protein-coupled receptor activity. Involved in G protein-coupled receptor signaling pathway; positive regulation of protein secretion; and sleep. Located in plasma membrane. Expressed in enteric muscle and neurons.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDST19F4.1a
T19F4.1b
T19F4.1c
Corresponding_CDS_historyT19F4.1a:wp261
Corresponding_transcriptT19F4.1a.1
T19F4.1b.1
T19F4.1c.1
Other_sequencePPC17509_1
JI174236.1
Oden_isotig19659
Dviv_isotig11885
Acan_isotig11359
Dviv_isotig22130
Dviv_isotig11883
Dviv_isotig11884
Dviv_isotig11882
Associated_featureWBsf1000377
WBsf1000378
WBsf1000379
WBsf1000380
WBsf1000381
WBsf1000382
WBsf1019868
WBsf1019869
WBsf1019870
WBsf231921
Experimental_infoRNAi_resultWBRNAi00072225Inferred_automaticallyRNAi_primary
WBRNAi00053558Inferred_automaticallyRNAi_primary
WBRNAi00018862Inferred_automaticallyRNAi_primary
WBRNAi00000682Inferred_automaticallyRNAi_primary
WBRNAi00113670Inferred_automaticallyRNAi_primary
WBRNAi00103535Inferred_automaticallyRNAi_primary
Expr_patternExpr13088
Expr1011653
Expr1157121
Expr2011900
Expr2030137
Drives_constructWBCnstr00025028
WBCnstr00038585
Construct_productWBCnstr00025028
Microarray_results (24)
Expression_clusterWBPaper00024970:GABAergic_neuron_specific
WBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:excretory-cell_larva_enriched
WBPaper00037950:excretory-cell_larva_SelectivelyEnriched
WBPaper00037950:GABAergic-motor-neurons_larva_SelectivelyEnriched
WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
WBPaper00042215:wdr-23(tm1817)_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00047132:glp-1(ts)-25C_upregulated
WBPaper00048988:neuron_enriched
WBPaper00048988:neuron_expressed
WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
WBPaper00050163:let-418(RNAi)_upregulated_24-cell-embryo
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050990:NMDA-neuron_enriched
WBPaper00050990:NMDA-neuron_expressed
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053810:daf-2(e1370)_upregulated
WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
WBPaper00055354:Rifampicin-Psora_downregulated
WBPaper00055386:daf-2(e1370)_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_upregulated_N2
WBPaper00056161:male_enriched_siRNA
WBPaper00057041:spc-1(cas971)_downregulated
WBPaper00057041:unc-70(cas983)_downregulated
WBPaper00058948:PA14_downregulated
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059754:E.faecalis_OG1RF_upregulated
WBPaper00059763:neuron_acr-2(n2420gf)_regulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060459:bcat-1(RNAi)_upregulated
WBPaper00060661:sensory-neuron_enriched
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00061081:E.faecalis_upregulated_N2
WBPaper00061340:AIY
WBPaper00061340:AIZ
WBPaper00061340:AVK
WBPaper00061340:CAN
WBPaper00061340:RIB
WBPaper00061424:Diet_MYb120_upregulated
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061527:xbx-3-DH11.5_20397
WBPaper00061995:mter-4(syb3662syb3403)_downregulated
WBPaper00062103:neuron_enriched
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062590:Aging_downregulated_body-wall-muscle
WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064661:lpd-3(ok2138)_upregulated
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
WBPaper00065749:Heat-Shock_downregulated_N2
WBPaper00065841:19_0
WBPaper00065841:28_0
WBPaper00065841:29_0
WBPaper00065841:69_0
WBPaper00065841:84_0
WBPaper00065841:85_0
WBPaper00065841:87_0
WBPaper00065841:96_0
WBPaper00065841:103_0
WBPaper00065841:107_0
WBPaper00065841:108_0
WBPaper00065841:112_0
WBPaper00065841:114_0
WBPaper00065841:115_0
WBPaper00065841:121_0
WBPaper00065841:122_0
WBPaper00065841:124_0
WBPaper00065841:125_0
WBPaper00065841:128_0
WBPaper00065841:133_0
WBPaper00065841:142_0
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066232:hsf-1(RNAi)_upregulated_WT
cgc4489_group_13
WBPaper00025141:N2_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00030839:Embryo_Pan_Neuronal
WBPaper00030839:Larval_Pan_Neuronal
WBPaper00030985:Photorhabdus_luminescens_upregulated
WBPaper00032948:StarveUp2
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_24h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_24h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00042548:miRISC_enriched
WBPaper00047070:N2_starvation_upregulated
WBPaper00048989:N2_allantoin_downregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
InteractionWBInteraction000356676
WBInteraction000559828
WBInteraction000559833
WBInteraction000563597
Map_infoMapVPosition0.389315
PositivePositive_cloneT19F4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00025071
WBPaper00032078
WBPaper00044852
WBPaper00050063
WBPaper00055865
WBPaper00065376
WBPaper00065946
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene