WormBase Tree Display for Gene: WBGene00020636
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| WBGene00020636 | SMap | S_parent | Sequence | T20H4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | ndus-8 | Person_evidence | WBPerson555 | |||||
| Sequence_name | T20H4.5 | ||||||||
| Molecular_name | T20H4.5 | ||||||||
| T20H4.5.1 | |||||||||
| CE00832 | |||||||||
| Other_name | CELE_T20H4.5 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | ndus-8 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:03 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 16 Jan 2023 18:37:21 | WBPerson51134 | Name_change | CGC_name | ndus-8 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ndus | ||||||||
| Allele (19) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Contained_in_operon | CEOP3424 | ||||||||
| Ortholog (38) | |||||||||
| Structured_description | Concise_description | T20H4.5 gene encodes a 23 kDa subunit of mitochondrial complex I that is required for oxidative phosphorylation and for resistance to volatile anesthetics; T20H4.5 is orthologous to human NADH-Ubiquinone oxidoreductase Fe-S protein 8 (NDUFS8); RNA interference screens indicate that it may be involved in longevity. | Paper_evidence | WBPaper00004637 | |||||
| WBPaper00028429 | |||||||||
| WBPaper00026643 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 15 Jun 2012 00:00:00 | ||||||||
| Automated_description | Predicted to enable 4 iron, 4 sulfur cluster binding activity; NADH dehydrogenase (ubiquinone) activity; and metal ion binding activity. Predicted to contribute to NADH dehydrogenase activity. Involved in mitochondrial electron transport, NADH to ubiquinone and response to xenobiotic stimulus. Located in mitochondrion. Used to study mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 2. Is an ortholog of human NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:700 | Homo sapiens | Paper_evidence | WBPaper00064182 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 11 Oct 2022 00:00:00 | ||||||||
| Potential_model | DOID:0112083 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7715) | |||||
| Models_disease_in_annotation | WBDOannot00001331 | ||||||||
| WBDOannot00001335 | |||||||||
| Molecular_info | Corresponding_CDS | T20H4.5 | |||||||
| Corresponding_transcript | T20H4.5.1 | ||||||||
| Other_sequence (109) | |||||||||
| Associated_feature | WBsf651188 | ||||||||
| WBsf992965 | |||||||||
| WBsf992966 | |||||||||
| WBsf1015204 | |||||||||
| WBsf1015205 | |||||||||
| WBsf1015206 | |||||||||
| WBsf226942 | |||||||||
| WBsf226943 | |||||||||
| WBsf226944 | |||||||||
| Experimental_info | RNAi_result (20) | ||||||||
| Expr_pattern | Expr1016049 | ||||||||
| Expr1038991 | |||||||||
| Expr1157229 | |||||||||
| Expr2006306 | |||||||||
| Expr2024526 | |||||||||
| Drives_construct | WBCnstr00024992 | ||||||||
| Construct_product | WBCnstr00024992 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (116) | |||||||||
| Interaction (131) | |||||||||
| Map_info | Map | III | Position | -0.767593 | |||||
| Positive | Positive_clone | T20H4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00003662 | ||||||||
| WBPaper00005928 | |||||||||
| WBPaper00028429 | |||||||||
| WBPaper00034662 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00056909 | |||||||||
| WBPaper00064182 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
