WormBase Tree Display for Gene: WBGene00021562
expand all nodes | collapse all nodes | view schema
| WBGene00021562 | SMap | S_parent | Sequence | CHROMOSOME_V | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 4 | |||||||
| Name | CGC_name | nuo-5 | Person_evidence | WBPerson1157 | |||||
| Sequence_name | Y45G12B.1 | ||||||||
| Molecular_name | Y45G12B.1 | ||||||||
| Y45G12B.1.1 | |||||||||
| CE21933 | |||||||||
| Other_name | nduf-1 | ||||||||
| ndus-1 | Person_evidence | WBPerson555 | |||||||
| CELE_Y45G12B.1 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | nuo-5 | ||||||||
| DB_info | Database | AceView | gene | 5D185 | |||||
| WormQTL | gene | WBGene00021562 | |||||||
| WormFlux | gene | WBGene00021562 | |||||||
| NDB | locus_tag | CELE_Y45G12B.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00021562|UniProtKB=Q9N4Y8 | |||||||
| family | PTHR11615 | ||||||||
| NCBI | gene | 178735 | |||||||
| RefSeq | protein | NM_071332.7 | |||||||
| TrEMBL | UniProtAcc | Q9N4Y8 | |||||||
| UniProt_GCRP | UniProtAcc | Q9N4Y8 | |||||||
| OMIM | gene | 157655 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:04 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 31 Aug 2005 14:07:05 | WBPerson2970 | Name_change | CGC_name | nuo-5 | ||||
| 3 | 26 Feb 2008 13:48:33 | WBPerson2970 | Name_change | Other_name | nduf-1 | ||||
| 4 | 16 Jan 2023 18:37:21 | WBPerson51134 | Name_change | Other_name | ndus-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nuo | ||||||||
| Allele (265) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00094987 | ||||||||
| 00094988 | |||||||||
| 00094989 | |||||||||
| 00094990 | |||||||||
| 00094991 | |||||||||
| 00094992 | |||||||||
| 00094993 | |||||||||
| 00125886 | |||||||||
| 00125887 | |||||||||
| 00125888 | |||||||||
| Contained_in_operon | CEOP5032 | ||||||||
| Ortholog (39) | |||||||||
| Paralog | WBGene00021902 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| Structured_description | Concise_description | nuo-5 is orthologous to human NADH-UBIQUINONE OXIDOREDUCTASE Fe-S PROTEIN 1 (NDUFS1; OMIM:157655), which when mutated leads to mitochondrial complex I deficiency. | Curator_confirmed | WBPerson1843 | |||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 23 Mar 2010 00:00:00 | ||||||||
| Automated_description | Predicted to enable 4 iron, 4 sulfur cluster binding activity; metal ion binding activity; and oxidoreductase activity, acting on NAD(P)H. Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in cellular respiration. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial respiratory chain complex I. Used to study mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 5. Is an ortholog of human NDUFS1 (NADH:ubiquinone oxidoreductase core subunit S1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:700 | Homo sapiens | Paper_evidence | WBPaper00064182 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 11 Oct 2022 00:00:00 | ||||||||
| Potential_model | DOID:0060536 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7707) | |||||
| DOID:0112068 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7707) | ||||||
| DOID:655 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7707) | ||||||
| Models_disease_in_annotation | WBDOannot00001329 | ||||||||
| WBDOannot00001333 | |||||||||
| Molecular_info | Corresponding_CDS | Y45G12B.1 | |||||||
| Corresponding_CDS_history | Y45G12B.1b:wp188 | ||||||||
| Y45G12B.1b:wp262 | |||||||||
| Y45G12B.1c:wp262 | |||||||||
| Corresponding_transcript | Y45G12B.1.1 | ||||||||
| Other_sequence (142) | |||||||||
| Associated_feature | WBsf661166 | ||||||||
| WBsf661167 | |||||||||
| WBsf661168 | |||||||||
| WBsf231531 | |||||||||
| WBsf231532 | |||||||||
| WBsf231533 | |||||||||
| WBsf231534 | |||||||||
| WBsf231535 | |||||||||
| Experimental_info | RNAi_result (13) | ||||||||
| Expr_pattern | Expr1012819 | ||||||||
| Expr1039440 | |||||||||
| Expr1160083 | |||||||||
| Expr2014531 | |||||||||
| Expr2032770 | |||||||||
| Microarray_results (30) | |||||||||
| Expression_cluster (123) | |||||||||
| Interaction (103) | |||||||||
| Map_info | Map | V | Position | -13.3131 | Error | 0.011997 | |||
| Positive | Positive_clone | Y45G12B | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (12) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
