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WormBase Tree Display for Gene: WBGene00021811

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Name Class

WBGene00021811SMapS_parentSequenceY53G8AR
IdentityVersion2
NameCGC_nameral-1
Sequence_nameY53G8AR.3
Molecular_nameY53G8AR.3a
Y53G8AR.3a.1
CE25424
Y53G8AR.3b
CE46416
Y53G8AR.3b.1
Other_nameY53G8AR.fCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_Y53G8AR.3Accession_evidenceNDBBX284603
Public_nameral-1
DB_infoDatabaseAceViewgene3E405
WormQTLgeneWBGene00021811
WormFluxgeneWBGene00021811
NDBlocus_tagCELE_Y53G8AR.3
PanthergeneCAEEL|WormBase=WBGene00021811|UniProtKB=H2L0Q6
familyPTHR24070
NCBIgene175433
RefSeqproteinNM_001267937.3
NM_001267938.2
TrEMBLUniProtAccQ9N3F8
H2L0Q6
UniProt_GCRPUniProtAccH2L0Q6
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:05WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
222 Dec 2004 08:58:44WBPerson2970Name_changeCGC_nameral-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classral
Allele (94)
Possibly_affected_byWBVar02152832
StrainWBStrain00051649
RNASeq_FPKM (74)
GO_annotation (23)
Ortholog (42)
Paralog (14)
Structured_descriptionAutomated_descriptionPredicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Involved in several processes, including determination of adult lifespan; multivesicular body assembly; and positive regulation of vulval development. Predicted to be located in plasma membrane. Expressed in several structures, including excretory canal; germ line; tail; vulva; and vulval precursor cell. Human ortholog(s) of this gene implicated in pancreatic ductal adenocarcinoma. Is an ortholog of human RALA (RAS like proto-oncogene A).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:3498Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9839)
DOID:4074Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9840)
Molecular_infoCorresponding_CDSY53G8AR.3a
Y53G8AR.3b
Corresponding_transcriptY53G8AR.3a.1
Y53G8AR.3b.1
Other_sequence (74)
Associated_feature (17)
Experimental_infoRNAi_resultWBRNAi00037442Inferred_automaticallyRNAi_primary
WBRNAi00085580Inferred_automaticallyRNAi_primary
WBRNAi00078603Inferred_automaticallyRNAi_primary
WBRNAi00057313Inferred_automaticallyRNAi_primary
WBRNAi00020954Inferred_automaticallyRNAi_primary
WBRNAi00078528Inferred_automaticallyRNAi_primary
WBRNAi00108135Inferred_automaticallyRNAi_primary
Expr_pattern (11)
Drives_constructWBCnstr00003754
WBCnstr00013840
WBCnstr00019548
WBCnstr00019552
WBCnstr00021261
WBCnstr00024429
Construct_productWBCnstr00019548
WBCnstr00019552
WBCnstr00021261
WBCnstr00021266
WBCnstr00024429
Microarray_results (20)
Expression_cluster (115)
Interaction (28)
Map_infoMapIIIPosition-7.28928Error0.018634
PositivePositive_cloneY53G8ARInferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5622
5488
Pseudo_map_position
Reference (27)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene