WormBase Tree Display for Gene: WBGene00022034
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| WBGene00022034 | SMap | S_parent | Sequence | Y65B4BL | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | deps-1 | Person_evidence | WBPerson632 | |||||
| Sequence_name | Y65B4BL.2 | ||||||||
| Molecular_name | Y65B4BL.2a | ||||||||
| Y65B4BL.2a.1 | |||||||||
| CE25536 | |||||||||
| Y65B4BL.2b | |||||||||
| CE49430 | |||||||||
| Y65B4BL.2b.1 | |||||||||
| Other_name | CELE_Y65B4BL.2 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | deps-1 | ||||||||
| DB_info | Database | AceView | gene | 1A981 | |||||
| WormQTL | gene | WBGene00022034 | |||||||
| WormFlux | gene | WBGene00022034 | |||||||
| NDB | locus_tag | CELE_Y65B4BL.2 | |||||||
| NCBI | gene | 171642 | |||||||
| RefSeq | protein | NM_058341.6 | |||||||
| NM_001306264.3 | |||||||||
| SwissProt | UniProtAcc | Q9N303 | |||||||
| UniProt_GCRP | UniProtAcc | Q9N303 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:05 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 10 May 2007 14:24:04 | WBPerson2970 | Name_change | CGC_name | deps-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | deps | ||||||||
| Allele (44) | |||||||||
| Strain | WBStrain00033258 | ||||||||
| WBStrain00034459 | |||||||||
| WBStrain00005683 | |||||||||
| WBStrain00022452 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00093439 | ||||||||
| 00093440 | |||||||||
| 00093441 | |||||||||
| 00093442 | |||||||||
| Ortholog (25) | |||||||||
| Structured_description | Concise_description | deps-1 encodes an large (619-residue), unfamiliar P-granule-associated protein required for germline RNAi, PGL-1's localization in P granules, accumulation of GLH-1 and RDE-4 (along with glh-1 mRNA), germline proliferation and fertility at high temperatures, and embryonic viability at low temperatures; unless rescued by maternal DEPS-1, deps-1 mutants show temperature-sensitive sterility at 24+ deg. C., but remain fertile at 15-20 deg. C.; DEPS-1 upregulates 13 germline-expressed genes (including glh-1, rde-4, aco-2, cts-1, plk-3, and deps-1 itself), and downregulates 32 such genes (including dyf-3, klp-10, pvf-1, rnh-1.3, and ugt-64); DEPS-1 has a C-terminal serine-rich domain, and has orthologs in other Caenorhabditis species, but has no non-nematode orthologs. | Paper_evidence | WBPaper00031477 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 15 Feb 2008 00:00:00 | ||||||||
| Automated_description | Predicted to be involved in regulatory ncRNA-mediated gene silencing. Located in P granule. Expressed in germ line and oocyte. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y65B4BL.2a | |||||||
| Y65B4BL.2b | |||||||||
| Corresponding_transcript | Y65B4BL.2a.1 | ||||||||
| Y65B4BL.2b.1 | |||||||||
| Other_sequence | Tcir_isotig05964 | ||||||||
| CRC07188_1 | |||||||||
| CBC04710_1 | |||||||||
| CR07679 | |||||||||
| Associated_feature | WBsf982516 | ||||||||
| WBsf982517 | |||||||||
| WBsf982518 | |||||||||
| WBsf217136 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00026908 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00026909 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00057910 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00024249 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00004770 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00023372 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00023885 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00057905 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00024172 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00033344 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr7892 | ||||||||
| Expr1018173 | |||||||||
| Expr1039687 | |||||||||
| Expr1161339 | |||||||||
| Expr2010859 | |||||||||
| Expr2029097 | |||||||||
| Regulate_expr_cluster | WBPaper00031477:Down_deps-1_vs_WT | ||||||||
| WBPaper00031477:Up_deps-1_vs_WT | |||||||||
| WBPaper00062123:DEPS-1_interacting | |||||||||
| Antibody | WBAntibody00001372 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (181) | |||||||||
| Interaction (156) | |||||||||
| Map_info | Map | I | Position | -18.9833 | Error | 0.006079 | |||
| Positive | Positive_clone | Y65B4BL | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00027804 | ||||||||
| WBPaper00031477 | |||||||||
| WBPaper00035324 | |||||||||
| WBPaper00043989 | |||||||||
| WBPaper00052166 | |||||||||
| WBPaper00057161 | |||||||||
| WBPaper00059254 | |||||||||
| WBPaper00060139 | |||||||||
| WBPaper00063892 | |||||||||
| WBPaper00064472 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
