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WormBase Tree Display for Gene: WBGene00022673

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Name Class

WBGene00022673SMapS_parentSequenceZK177
IdentityVersion2
NameCGC_namesahd-1Person_evidenceWBPerson555
Sequence_nameZK177.8
Molecular_name (18)
Other_nameCELE_ZK177.8Accession_evidenceNDBBX284602
Public_namesahd-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:06WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
213 Oct 2023 01:37:05WBPerson51134Name_changeCGC_namesahd-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsahd
Allele (76)
StrainWBStrain00001464
WBStrain00001188
WBStrain00003484
RNASeq_FPKM (74)
GO_annotation (18)
Ortholog (41)
Structured_descriptionAutomated_descriptionEnables dGTPase activity; deoxynucleoside triphosphate hydrolase activity; and protein homodimerization activity. Involved in dGTP catabolic process. Predicted to be located in nucleus. Expressed in head and tail. Human ortholog(s) of this gene implicated in several diseases, including Aicardi-Goutieres syndrome; Chilblain lupus; and hepatitis B. Is an ortholog of human SAMHD1 (SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0060386Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:15925)
DOID:0050629Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:15925)
DOID:1883Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:15925)
DOID:9119Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:15925)
DOID:2043Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:15925)
Molecular_infoCorresponding_CDSZK177.8a
ZK177.8b
ZK177.8c
ZK177.8d
ZK177.8e
Corresponding_transcriptZK177.8a.1
ZK177.8a.2
ZK177.8b.1
ZK177.8b.2
ZK177.8b.3
ZK177.8c.1
ZK177.8d.1
ZK177.8e.1
Other_sequence (21)
Associated_featureWBsf650067
WBsf665533
WBsf665534
WBsf987898
WBsf223057
WBsf223058
Experimental_infoRNAi_resultWBRNAi00001766Inferred_automaticallyRNAi_primary
WBRNAi00038219Inferred_automaticallyRNAi_primary
WBRNAi00059260Inferred_automaticallyRNAi_primary
WBRNAi00021902Inferred_automaticallyRNAi_primary
Expr_pattern (11)
Drives_constructWBCnstr00002080
WBCnstr00003942
WBCnstr00004214
WBCnstr00024061
Construct_productWBCnstr00024061
Microarray_results (32)
Expression_cluster (148)
Interaction (24)
Map_infoPositivePositive_cloneZK177Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionII-1.22624
ReferenceWBPaper00038491
WBPaper00055090
WBPaper00065885
MethodGene