WormBase Tree Display for Gene: WBGene00022797

WBGene00022797 SMap: S_parent: Sequence: ZK688
  Identity: Version: 2
    Name: CGC_name: best-24 Person_evidence: WBPerson260
      Sequence_name: ZK688.2
      Molecular_name: ZK688.2
        ZK688.2.1
        CE00460
      Other_name: CELE_ZK688.2 Accession_evidence: NDB BX284603
      Public_name: best-24
    DB_info: Database: AceView gene 3I993
        WormQTL gene WBGene00022797
        WormFlux gene WBGene00022797
        NDB locus_tag CELE_ZK688.2
        Panther gene CAEEL|WormBase=WBGene00022797|UniProtKB=P34672
          family PTHR10736
        NCBI gene 176110
        RefSeq protein NM_066316.8
        SwissProt UniProtAcc P34672
        UniProt_GCRP UniProtAcc P34672
        OMIM gene 607854
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:06 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 07 Feb 2012 16:30:56 WBPerson2970 Name_change: CGC_name: best-24
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: best
    Allele (38)
    Strain: WBStrain00003420
      WBStrain00051454
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog (46)
    Paralog (26)
    Structured_description: Automated_description: Predicted to enable chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Expressed in head neurons; hypodermis; intestine; and nervous system. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy and retinal degeneration (multiple). Is an ortholog of human BEST2 (bestrophin 2) and BEST4 (bestrophin 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0110396 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:4448 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:0050661 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:0050662 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
      DOID:0111569 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12703)
  Molecular_info: Corresponding_CDS: ZK688.2
    Corresponding_transcript: ZK688.2.1
    Other_sequence (28)
    Associated_feature: WBsf993187
      WBsf225297
      WBsf225298
  Experimental_info: RNAi_result: WBRNAi00070770 Inferred_automatically: RNAi_primary
      WBRNAi00066737 Inferred_automatically: RNAi_primary
      WBRNAi00066550 Inferred_automatically: RNAi_primary
      WBRNAi00005215 Inferred_automatically: RNAi_primary
      WBRNAi00038421 Inferred_automatically: RNAi_primary
      WBRNAi00059670 Inferred_automatically: RNAi_primary
      WBRNAi00070771 Inferred_automatically: RNAi_primary
      WBRNAi00022133 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram344
      Expr7243
      Expr1018157
      Expr1040085
      Expr1163085
      Expr2009606
      Expr2027843
    Drives_construct: WBCnstr00003887
      WBCnstr00023966
    Construct_product: WBCnstr00023966
    Microarray_results (19)
    Expression_cluster (184)
    Interaction (29)
  Map_info: Map: III Position: -0.5041
    Positive: Positive_clone: ZK688 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene