WormBase Tree Display for Gene: WBGene00023498
expand all nodes | collapse all nodes | view schema
| WBGene00023498 | SMap | S_parent | Sequence | ZK678 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | lin-15A | Person_evidence | WBPerson261 | |||||
| Sequence_name | ZK678.1 | ||||||||
| Molecular_name | ZK678.1 | ||||||||
| ZK678.1.1 | |||||||||
| CE15383 | |||||||||
| Other_name | lin-15 | CGC_data_submission | |||||||
| CELE_ZK678.1 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | lin-15A | ||||||||
| DB_info | Database | AceView | gene | XQ353 | |||||
| WormQTL | gene | WBGene00023498 | |||||||
| SignaLink | protein | WBGene00023498 | |||||||
| WormFlux | gene | WBGene00023498 | |||||||
| NDB | locus_tag | CELE_ZK678.1 | |||||||
| NCBI | gene | 181663 | |||||||
| RefSeq | protein | NM_078187.8 | |||||||
| SwissProt | UniProtAcc | Q27365 | |||||||
| TREEFAM | TREEFAM_ID | TF336904 | |||||||
| UniProt_GCRP | UniProtAcc | Q27365 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 24 Aug 2004 16:05:45 | WBPerson1971 | Event | Split_from | WBGene00003004 | ||||
| Split_from | WBGene00003004 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lin | ||||||||
| Reference_allele | WBVar00089409 | ||||||||
| Allele (85) | |||||||||
| Legacy_information (3) | |||||||||
| Strain (185) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Contained_in_operon | CEOPX140 | ||||||||
| Ortholog (18) | |||||||||
| Structured_description | Concise_description | lin-15A encodes a novel protein that contains a THAP zinc-finger-like (C2CH) motif; LIN-15A activity is required non-cell autonomously to negatively regulate vulval development; genetic analysis indicates that lin-15A, a class A synMuv gene, functions upstream of the LIN-3 EGF and the LET-23 EGFR and redundantly with class B synMuv genes such as lin-15B and lin-35 Rb and class C synMuv genes such as trr-1 and mys-1 to regulate vulval development; genetic mosaic analysis suggests that, in regulating vulval development, LIN-15A functions outside of the six vulval precursor cells P(3-8).p, likely acting instead in the surrounding hypodermal tissue; LIN-15A is a broadly expressed nuclear protein whose normal expression depends upon LIN-56, an additional THAP motif-containing protein, with which LIN-15A physically interacts. | Paper_evidence | WBPaper00001360 | |||||
| WBPaper00001949 | |||||||||
| WBPaper00001990 | |||||||||
| WBPaper00013412 | |||||||||
| WBPaper00037906 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 04 Mar 2011 00:00:00 | ||||||||
| Automated_description | Involved in several processes, including negative regulation of vulval development; protein stabilization; and vulval development. Located in nucleus. Expressed in gonad. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | ZK678.1 | |||||||
| Corresponding_transcript | ZK678.1.1 | ||||||||
| Other_sequence | BE239237.1 | ||||||||
| OVC06601_1 | |||||||||
| Associated_feature | WBsf236809 | ||||||||
| WBsf236810 | |||||||||
| Experimental_info | RNAi_result (47) | ||||||||
| Expr_pattern | Expr13101 | ||||||||
| Expr1026271 | |||||||||
| Expr1040141 | |||||||||
| Expr1163064 | |||||||||
| Expr2013161 | |||||||||
| Expr2031393 | |||||||||
| Drives_construct | WBCnstr00023854 | ||||||||
| Construct_product | WBCnstr00016646 | ||||||||
| WBCnstr00019445 | |||||||||
| WBCnstr00019587 | |||||||||
| WBCnstr00019645 | |||||||||
| WBCnstr00020631 | |||||||||
| WBCnstr00023854 | |||||||||
| Antibody | WBAntibody00002219 | ||||||||
| WBAntibody00002253 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (134) | |||||||||
| Interaction (321) | |||||||||
| Map_info | Map | X | Position | 22.9459 | Error | 0.001185 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | PS#74B3 | |||||||
| ZK678 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Mapping_data | 2_point | 4458 | |||||||
| 4457 | |||||||||
| 6060 | |||||||||
| 7015 | |||||||||
| 7082 | |||||||||
| Multi_point | 5356 | ||||||||
| Pos_neg_data | 4461 | ||||||||
| 491 | |||||||||
| 518 | |||||||||
| 519 | |||||||||
| 536 | |||||||||
| Landmark_gene | |||||||||
| Reference (300) | |||||||||
| Remark | To properly reflect that this locus encodes two distinct products, this gene was created from the former lin-15 gene on the advice of the CGC. [krb 040824] | ||||||||
| Method | Gene |
