WormBase Tree Display for Gene: WBGene00043948

WBGene00043948 SMap: S_parent: Sequence: R05D3
  Identity: Version: 2
    Name: Sequence_name: ZC262.7
      Molecular_name: ZC262.7
        ZC262.7.1
        CE40675
      Other_name: CELE_ZC262.7 Accession_evidence: NDB BX284603
      Public_name: ZC262.7
    DB_info: Database: AceView gene 3J432
        NDB locus_tag CELE_ZC262.7
        NCBI gene 24105263
        RefSeq protein NM_001306707.1
        TrEMBL UniProtAcc E9P841
        UniProt_GCRP UniProtAcc E9P841
        OMIM gene 602821
            604593
    Species: Caenorhabditis elegans
    History: Version_change: 1 04 Oct 2004 10:58:10 WBPerson1971 Event: Created
                Killed
        2 26 Apr 2006 13:33:25 WBPerson1867 Event: Resurrected
    Status: Live: Curator_confirmed: WBPerson1867
  Gene_info: Biotype: SO:0001217
    Allele (21)
    RNASeq_FPKM (74)
    Contained_in_operon: CEOP3874
    Ortholog (38)
    Paralog (19)
    Structured_description: Automated_description: Enriched in F cell and U cell based on single-cell RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and alg-1 based on RNA-seq; proteomic; and microarray studies. Is affected by six chemicals including nicotine; Sodium Chloride; and Psoralens based on proteomic and RNA-seq studies. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 3; asbestos-related lung carcinoma; autoimmune disease (multiple); and complex cortical dysplasia with other brain malformations 2. Human KIF5B enables identical protein binding activity; microtubule binding activity; and microtubule motor activity. Is an ortholog of human KIF5A (kinesin family member 5A); KIF5B (kinesin family member 5B); and KIF5C (kinesin family member 5C). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:7148 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6323)
      DOID:0090133 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6325)
      DOID:2377 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6323)
      DOID:127 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6325)
      DOID:7596 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6323)
      DOID:0110042 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6325)
      DOID:10283 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6323)
      DOID:0081379 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6323)
      DOID:0110763 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6323)
      DOID:5419 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6325)
  Molecular_info: Corresponding_CDS: ZC262.7
    Corresponding_CDS_history: ZC262.7:wp68
    Corresponding_transcript: ZC262.7.1
    Other_sequence (15)
  Experimental_info: RNAi_result (30)
    Expr_pattern: Expr1023026
      Expr1162257
      Expr2008594
      Expr2026830
    Drives_construct: WBCnstr00023820
    Construct_product: WBCnstr00023820
    Microarray_results (12)
    Expression_cluster (45)
  Map_info: Positive: Positive_clone: ZC262 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: III -0.328521
  Remark: The corresponding CDS object for this gene had been created and removed before WormBase introduced the concept of unique gene identifiers. This (dead) gene object exists as an attempt to make sure that a gene ID exists for every worm gene prediction that has ever existed. Curator_confirmed: WBPerson1971
    [050610 pad] Automatic assignment of Sequence_name connection using info taken from Public_name tags.
    This gene was mistakenly killed so has been resurrected. Curator_confirmed: WBPerson1867
  Method: Gene