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WormBase Tree Display for Gene: WBGene00044621

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Name Class

WBGene00044621SMapS_parentSequenceF53B1
IdentityVersion2
NameCGC_namebus-5Person_evidenceWBPerson261
Sequence_nameF53B1.4
Molecular_nameF53B1.4
F53B1.4.1
CE04644
Other_nameCELE_F53B1.4Accession_evidenceNDBBX284606
Public_namebus-5
DB_infoDatabaseNDBlocus_tagCELE_F53B1.4
NCBIgene180525
RefSeqproteinNM_075989.3
TREEFAMTREEFAM_IDTF313892
TrEMBLUniProtAccQ20697
UniProt_GCRPUniProtAccQ20697
OMIMgene616146
SpeciesCaenorhabditis elegans
HistoryVersion_change101 Sep 2005 10:24:02WBPerson2970EventCreated
230 Jul 2020 16:54:45WBPerson1983EventAcquires_mergeWBGene00018737
Acquires_mergeWBGene00018737
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classbus
Reference_alleleWBVar00144919
AlleleWBVar00144919Inferred_automaticallyFrom strain object: CB5612
WBVar00144932Inferred_automaticallyFrom strain object: CB5614
WBVar02148835Inferred_automaticallyFrom strain object: CB6991
From strain object: CB6992
From strain object: DC19
WBVar02148846Inferred_automaticallyFrom strain object: CB7448
WBVar00144930
WBVar00144935
WBVar00144917
WBVar00144916
WBVar00145006
WBVar00145001
WBVar02157997
WBVar01619199
WBVar01619200
WBVar01619201
WBVar00496050
WBVar00496051
WBVar00496052
WBVar00496053
WBVar01499751
WBVar01499636
WBVar00075758
WBVar01987270
WBVar01124450
WBVar01124451
WBVar01124452
WBVar01124453
WBVar01124454
WBVar01124455
WBVar01124456
WBVar01124457
WBVar01124458
WBVar01124459
WBVar01124460
WBVar01124461
WBVar01124462
WBVar01124463
WBVar01124464
StrainWBStrain00004659
WBStrain00004661
WBStrain00004730
WBStrain00004731
WBStrain00004762
WBStrain00005604
RNASeq_FPKM (74)
Ortholog (30)
Paralog (13)
Structured_descriptionConcise_descriptionbus-5 is an uncloned gene required for colonization by Microbacterium nematophilum, the tail-swelling response to M. nematophilum infection, and for fully normal cuticle antigens and traction during movement; bus-5 is also strongly required for cuticle integrity and for long-term survival during starvation.Paper_evidenceWBPaper00026735
WBPaper00029153
Curator_confirmedWBPerson567
Date_last_updated16 Jul 2007 00:00:00
Automated_descriptionExpressed in hyp7 syncytium; hypodermal cell; and seam cell. Human ortholog(s) of this gene implicated in Catel Manzke syndrome. Is predicted to encode a protein with the following domains: NAD(P)-binding domain; NAD(P)-binding domain superfamily; and GDP-mannose 4,6 dehydratase. Is an ortholog of human TGDS (TDP-glucose 4,6-dehydratase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0081122Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:20324)
Molecular_infoCorresponding_CDSF53B1.4
Corresponding_transcriptF53B1.4.1
Other_sequence (57)
Associated_featureWBsf237051
WBsf237052
Experimental_infoRNAi_resultWBRNAi00015469Inferred_automaticallyRNAi_primary
WBRNAi00032665Inferred_automaticallyRNAi_primary
WBRNAi00025578Inferred_automaticallyRNAi_primary
WBRNAi00048070Inferred_automaticallyRNAi_primary
WBRNAi00025577Inferred_automaticallyRNAi_primary
WBRNAi00027359Inferred_automaticallyRNAi_primary
Expr_patternExpr15742
Expr15743
Expr15744
Expr16442
Expr1014478
Expr1038066
Expr1151881
Expr2004032
Expr2022254
Drives_constructWBCnstr00026306
WBCnstr00042503
WBCnstr00042504
WBCnstr00043024
Construct_productWBCnstr00026306
Microarray_results (18)
Expression_cluster (268)
InteractionWBInteraction000538982
WBInteraction000558533
WBInteraction000565990
WBInteraction000576110
WBInteraction000576669
WBInteraction000579498
WBProcessWBbiopr:00000039
Map_infoMapXPosition-17.0437
PositivePositive_cloneF53B1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5461
Reference (12)
Remark[2020-07-30T16:54:45.386Z WBPerson1983] Gene Merged: bus-5 confirmed as this sequenced loci also known as rml-2Curator_confirmedWBPerson1983
MethodGene