WormBase Tree Display for Gene: WBGene00044623

WBGene00044623 SMap: S_parent: Sequence: T23F2
  Identity: Version: 5
    Name: CGC_name: bus-8B Person_evidence: WBPerson261
      Sequence_name: T23F2.1
      Molecular_name: T23F2.1a
        T23F2.1a.1
        CE28488
        T23F2.1b
        CE54583
        T23F2.1b.1
      Other_name: tag-249
        nic-1 Paper_evidence: WBPaper00031667
        phi-42 Person_evidence: WBPerson2582
        CELE_T23F2.1 Accession_evidence: NDB BX284606
      Public_name: bus-8B
    DB_info: Database: WormQTL gene WBGene00044623
        WormFlux gene WBGene00044623
        NDB locus_tag CELE_T23F2.1
        Panther gene CAEEL|WormBase=WBGene00044623|UniProtKB=G5ECB6
          family PTHR45918
        NCBI gene 180821
        RefSeq protein NM_001421340.1
            NM_076531.8
        KEGG KEGG_id 2.4.1.257
        NemaPath KEGG_id 2.4.1.257
        TrEMBL UniProtAcc G5ECB6
        UniProt_GCRP UniProtAcc G5ECB6
    Species: Caenorhabditis elegans
    History: Version_change: 1 01 Sep 2005 10:24:02 WBPerson2970 Event: Created
        2 18 Apr 2008 09:35:23 WBPerson2970 Event: Acquires_merge: WBGene00020734
              Name_change: Sequence_name: T23F2.1
                Other_name: tag-249
        3 18 Apr 2008 09:36:02 WBPerson2970 Event: Acquires_merge: WBGene00003737
              Name_change: Other_name: nic-1
        4 02 Mar 2018 11:09:16 WBPerson4025 Event: Split_into: WBGene00303081
        5 05 May 2023 12:43:53 WBPerson51134 Name_change: CGC_name: bus-8B
      Acquires_merge: WBGene00003737
        WBGene00020734
      Split_into: WBGene00303081
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: bus
    Reference_allele: WBVar00144929
    Allele (63)
    RNASeq_FPKM (74)
    GO_annotation (14)
    Ortholog (28)
    Paralog: WBGene00017282 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00008431 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00015162 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: bus-8 encodes a glycosyltransferase related to mannosyltransferases that play a role in protein N-linked glycosylation ; bus-8 is required for colonization by Microbacterium nematophilum and the tail-swelling response to M. nematophilum infection; bus-8 is also essential for enclosure during embryonic morphogenesis, functioning in or with ephrin-mediated signaling to effect the proper neuroblast organization that facilitates epidermal migration; bus-8 is also required for cuticle integrity, normal cuticle antigens, completely normal traction during movement, and viability; a BUS-8::GFP fusion protein is detected during embryonic morphogenesis in cells underlying the ventral epidermis (possibly neuroblasts), subsequent expression is then restricted to the hypodermal seam cells which continues throughout postembryonic development. Paper_evidence: WBPaper00026735
            WBPaper00029153
            WBPaper00031667
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 21 Aug 2009 00:00:00
      Automated_description: Predicted to enable alpha-1,3-mannosyltransferase activity. Predicted to be involved in oligosaccharide-lipid intermediate biosynthetic process. Predicted to be located in membrane. Expressed in seam cell. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: T23F2.1a
      T23F2.1b
    Corresponding_CDS_history: T23F2.1a:wp264
      T23F2.1b:wp264
    Corresponding_transcript: T23F2.1a.1
      T23F2.1b.1
    Other_sequence (16)
    Associated_feature: WBsf648126
      WBsf648127
      WBsf648128
      WBsf662804
      WBsf1005280
      WBsf1022960
      WBsf235733
      WBsf235734
      WBsf235735
  Experimental_info: RNAi_result (12)
    Expr_pattern: Expr8071
      Expr1025665
      Expr1040291
      Expr1157491
      Expr2009690
      Expr2027929
    Drives_construct: WBCnstr00013089
      WBCnstr00037810
    Construct_product: WBCnstr00013089
      WBCnstr00037810
    Microarray_results (21)
    Expression_cluster: WBPaper00032528:L3_enriched
      WBPaper00035197:fer-1_downregulated
      WBPaper00037682:sma-2_sma-4_upregulated
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040285:H2S_24hr_downregulated
      WBPaper00041954:ethanol_upregulated
      WBPaper00043945:MeHg_upregulated
      WBPaper00044260:1-methylnicotinamide_upregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044786:emr-1(gk119)_upregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00044786:lem-2(tm1582)_upregulated
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00046121:ecdoderm_unique
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046805:csr-1(RNAi)_downregulated_Set1
      WBPaper00046887:WNT-target
      WBPaper00048988:neuron_expressed
      WBPaper00049018:swsn-2.2(RNAi)_downregulated
      WBPaper00049498:npr-1(ur89)_regulated_4
      WBPaper00049594:osm-9(ok1677)_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050121:mir-60(n4947)_upregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
      WBPaper00050163:chd-3(eh4)_upregulated_100-cell-embryo
      WBPaper00050182:lmn-1(L535P)_upregulated
      WBPaper00050332:skn-1(RNAi)_downregulated
      WBPaper00050332:skr-1(RNAi)-skr-2(RNAi)_downregulated
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050843:sesamin_downregulated
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00051352:Long-Term-Association-Memory_upregulated
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053020:sid-3(ok973)_upregulated
      WBPaper00053020:sta-1(ok587)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053402:cco-1(RNAi)_downregulated
      WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00054410:set-9(rw5)_downregulated
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055013:hmg-3(bar24)_downregulated
      WBPaper00055013:hmg-4(RNAi)_downregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Metformin_upregulated
      WBPaper00055354:Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin_upregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055941:nuo-6(qm200)_downregulated
      WBPaper00055944:C.butyricum_vs_OP50_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00055981:fog-2(q71)_downregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056090:hpx-2(dg047)_upregulated_E.Coli
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056165:MINA-1_interacting_mRNA
      WBPaper00056169:rrf-3(pk1426)_downregulated_adult
      WBPaper00056169:rrf-3(pk1426)_downregulated_L3
      WBPaper00056169:rrf-3(pk1426)_downregulated_L4
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056290:mdt-15(mg584)_upregulated
      WBPaper00056330:glycine_downregulated
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057068:ints-4(RNAi)_downregulated
      WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
      WBPaper00057068:numr-1(RNAi)_downregulated
      WBPaper00057347:nhr-14(tm1473)_downreglated
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058711:skn-1(lax188)_upregulated
      WBPaper00058948:npr-8(ok1439)_downregulated_OP50
      WBPaper00058948:PA14_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059231:alh-6(lax105)_L4_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059421:daf-1(m40);daf-3(mgDf90)_downregulated
      WBPaper00059421:daf-3(mgDf90)_downregulated
      WBPaper00059567:olrn-1(ums9)_regulated
      WBPaper00059605:mut-16(pk710)_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060273:vrk-1(RNAi)_downregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_downregulated_CoCl2_6hr
      WBPaper00060445:ikb-1(nr2027)_downregulated_L4
      WBPaper00060445:nfki-1(cer1)_downregulated_L4
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060886:spr-5(by101);met-2(n4256)_downregulated
      WBPaper00060886:spr-5(by101)_downregulated
      WBPaper00060909:atfs-1(et18)_downregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:HB115_upregulated
      WBPaper00061007:M.braciatum_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061040:FW1256_downregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061081:skpo-1(ok1640)_upregulated_OP50
      WBPaper00061106:endu-2(tm4977)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061274:hypergravity_15xg_upregulated
      WBPaper00061340:Seam_cell
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:agmo-1_5527-F53B1.4
      WBPaper00061527:bus-8_3160-K04H4.2_2324
      WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated
      WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00061952:daf-18(nr2037)_upregulated
      WBPaper00061995:mter-4(syb3662syb3403)_downregulated
      WBPaper00062156:jmjd-1.2(zr1010)_upregulated
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:etr-1(lq61)_upregulated
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062456:doxycycline_upregulated_N2_transcript
      WBPaper00062497:xpf-1(tm2842)_upregulated
      WBPaper00062534:fat-P-80_downregulated
      WBPaper00062534:fat-P-80_downregulated_ech-6(RNAi)
      WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
      WBPaper00062715:blmp-1(s71)_upregulated
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064403:Heat-killed-E.Coli_upregulated
      WBPaper00064661:lpd-3(ok2138)_upregulated
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064841:tent-5(tm3504)_downregulated_transcript
      WBPaper00064999:miR-229-64-65-66_upregulated
      WBPaper00065560:E.coli-HB101_downregulated_F3
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00065749:endu-2(tm4977)_upregulated
      WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
      WBPaper00065749:Heat-Shock_downregulated_N2
      WBPaper00065841:13_0
      WBPaper00065841:38_0
      WBPaper00065841:89_0
      WBPaper00065945:global-rpoa-2(-)_downregulated_transcript
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00066004:tdp-1(csb38)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      cgc4386_cluster_5_6
      cgc4489_group_2
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025032:cluster_83
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Enriched_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026952:class_E
      WBPaper00030839:Embryo_A_Class
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031184:acrylamide_downregulated
      WBPaper00031832:slr-2_regulated
      WBPaper00032948:FedUp
      WBPaper00032948:MoltOssilate
      WBPaper00034739:N2lessDR1350
      WBPaper00034739:RIL17lessRIL14
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_E
      WBPaper00038060:SUMO-1_downregulated
      WBPaper00038172:crh-1null_down_regulated
      WBPaper00038172:tax-6null_down_regulated
      WBPaper00038304:octr-1_regulated
      WBPaper00040116:pRJ-FR.5_down_regulated
      WBPaper00040185:nhr-23(RNAi)_downregulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5
      WBPaper00040876:mir-35_downregulated
      WBPaper00040963:Q100_down
      WBPaper00040963:Q200_down
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042258:DA1877_downregulated_YoungAdult
      WBPaper00045374:Benzene_downregulated
      WBPaper00045437:Toxic-Se_downregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00045865:biofilm_downregulated_B
      WBPaper00046083:oga-1(ok1207)_OP50_downregulated
      WBPaper00046083:ogt-1(ok1474)_OP50_downregulated
      WBPaper00046083:pmk-1(km25)_OP50_downregulated
      WBPaper00046548:dafachronic-acid_upregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00047070:N2_UV_downregulated
      WBPaper00047070:xpa-1_UV_downregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00049311:sAg-MNP_regulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc6390]:Cluster_B
    SAGE_tag (11)
    Interaction (200)
    WBProcess: WBbiopr:00000039
  Map_info: Map: X Position: -5.24205 Error: 0.029229
    Positive: Positive_clone: T23F2 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5464
        5465
        5224
        4261
  Reference (37)
  Method: Gene