WormBase Tree Display for Gene: WBGene00044760

WBGene00044760 SMap: S_parent: Sequence: Y71H2AM
  Identity: Version: 1
    Name: Sequence_name: Y71H2AM.25
      Molecular_name: Y71H2AM.25
        Y71H2AM.25.1
        CE39981
      Other_name: CELE_Y71H2AM.25 Accession_evidence: NDB BX284603
      Public_name: Y71H2AM.25
    DB_info: Database: AceView gene 3D897
        WormFlux gene WBGene00044760
        NDB locus_tag CELE_Y71H2AM.25
        Panther gene CAEEL|WormBase=WBGene00044760|UniProtKB=Q2AAB9
          family PTHR12411
        NCBI gene 4363054
        RefSeq protein NM_001047422.5
        TREEFAM TREEFAM_ID TF322370
        TrEMBL UniProtAcc Q2AAB9
        UniProt_GCRP UniProtAcc Q2AAB9
        OMIM gene 601105
    Species: Caenorhabditis elegans
    History: Version_change: 1 24 Feb 2006 13:40:14 WBPerson1867 Event: Split_from: WBGene00022168
      Split_from: WBGene00022168
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (21)
    RNASeq_FPKM (74)
    GO_annotation: 00080262
      00080263
      00080264
      00080265
      00146128
      00146129
    Ortholog (56)
    Paralog (29)
    Structured_description: Automated_description: Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Down syndrome; cerebrovascular disease (multiple); and pycnodysostosis. Is an ortholog of human CTSK (cathepsin K) and CTSS (cathepsin S). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2545)
      DOID:2378 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2545)
      DOID:3407 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2545)
      DOID:14250 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2545)
      DOID:870 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2545)
      DOID:0080038 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2536)
      DOID:10941 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2536,HGNC:2545)
  Molecular_info: Corresponding_CDS: Y71H2AM.25
    Corresponding_transcript: Y71H2AM.25.1
    Other_sequence: MH03087
  Experimental_info: RNAi_result: WBRNAi00115196 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1161665
      Expr2008323
      Expr2026563
    Microarray_results: A_12_P144545
      GPL19516_CGZ0053030
      GPL21109_Y71H2AM.25
      GPL8304_CE_WBGene00044760_A
      GPL8673_Y71H2AM_25P00304
      GPL8673_Y71H2AM_25P00418
      GPL8673_Y71H2AM_25P00439
    Expression_cluster (102)
  Map_info: Positive: Positive_clone: Y71H2AM Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: III -10.0956
  Reference: WBPaper00038491
    WBPaper00055090
  Method: Gene