WormBase Tree Display for Interaction: WBInteraction000502385
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| WBInteraction000502385 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00000501 | Interactor_type | Trans_regulated | |
| Expr_pattern | Expr961 | ||||
| Transgene | WBTransgene00004909 | ||||
| Construct | WBCnstr00004890 | ||||
| WBGene00006831 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00143874 | Interactor_type | Trans_regulator | ||
| Interaction_summary | When expressed in the unc-104 (e1265) mutant background, CHO-1:GFP failed to localize synaptically, and was retained in the neuronal cell bodies. | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [cho-1::gfp], translational fusion | ||||
| Transgene | |||||
| Regulation_level | Post_transcriptional | ||||
| Regulation_result | Positive_regulate | Anatomy_term | WBbt:0006840 | ||
| Subcellular_localization | CHO-1:GFP localized to axonal varicosities and colocalized with a fluorescent reporter of the synaptic vesicle marker synaptobrevin. | ||||
| Paper | WBPaper00027671 | ||||
| Remark | CHO-1, like mouse CHT, uses axonal transport mechanisms common to other synaptic vesicle proteins. |
