WormBase Tree Display for Interaction: WBInteraction000502771
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| WBInteraction000502771 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Change_of_expression_level | |||||
| Interactor | Interactor_overlapping_gene | WBGene00003001 | Interactor_type | Trans_regulated | |
| Expr_pattern | Expr544 | ||||
| Transgene | WBTransgene00000048 | ||||
| Construct | WBCnstr00000048 | ||||
| WBGene00004760 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00000238 | Interactor_type | Trans_regulator | ||
| Interaction_summary | In sel-2(+), LIN-12::GFP was mostly at the apical surface of the VPCs or in puncta close to the apical surface. In sel-2(-), LIN-12::GFP was not restricted to the apical surface but was also present basolaterally. In addition to being mislocalized to the basolateral surface, the overall level of LIN-12::GFP was elevated in sel-2(-). | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [lin-12::gfp], LIN-12::GFP under the control of lin-12 regulatory sequences. | ||||
| Transgene | |||||
| Regulation_result | Positive_regulate | Anatomy_term | WBbt:0008121 | ||
| WBbt:0008125 | |||||
| WBbt:0008129 | |||||
| Subcellular_localization | apical surface of the VPCs | ||||
| Paper | WBPaper00028987 | ||||
| Antibody_remark | anti-GFP (Molecular Probes) |
