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WormBase Tree Display for Interaction: WBInteraction000504091

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Name Class

WBInteraction000504091Interaction_typeRegulatory
InteractorInteractor_overlapping_geneWBGene00006364Interactor_typeTrans_regulator
WBGene00006831Interactor_typeTrans_regulated
Variation_interactorWBVar00088146Interactor_typeTrans_regulator
WBVar00091522Interactor_typeTrans_regulator
Interaction_summaryUNC-104 activity is decreased in syd-2 mutants and switches from anterograde-based to retrograde- based movements. Indeed, motor particles exhibited increased net retrograde movements in syd-2 from a predominantly anterograde directionality in wild-type. Similarly, the total net transport (i.e., net displacement over one particle track) is decreased for antero- grade events and increased in retrograde directions with a stronger phenotype in syd-2(ok217) (SYD-2 null) than in syd-2(ju37) (C- terminal truncated SYD-2).
PaperWBPaper00035430