WormBase Tree Display for Interaction: WBInteraction000504351
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| WBInteraction000504351 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00011979 | Interactor_type | Trans_regulated | |
| Transgene | WBTransgene00005978 | ||||
| Construct | WBCnstr00005842 | ||||
| WBGene00000223 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00278489 | Interactor_type | Trans_regulator | ||
| Interaction_summary | The atf-7(qd22) mutant exhibited a marked decrease in expression of the pmk-1-regulated gene, T24B8.5, encoding a ShK-like toxin peptide, fused to green fluorescent protein (GFP) and provides an in vivo sensor of PMK-1 pathway activity. | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [T24B8.5::gfp], transcriptional fusion. | ||||
| Transgene | |||||
| Regulation_level | Post_translational | ||||
| Regulation_result | Positive_regulate | Anatomy_term | WBbt:0005772 | ||
| Paper | WBPaper00036086 | ||||
| Remark | qd22 is a gain-of-function allele of atf-7. |
