WormBase Tree Display for Interaction: WBInteraction000524143
expand all nodes | collapse all nodes | view schema
WBInteraction000524143 | Interaction_type | Genetic | Unilateral_suppression | ||
---|---|---|---|---|---|
GI_module_one | Mono_phenotypic | ||||
GI_module_two | Suppressing | ||||
Interactor | Interactor_overlapping_gene | WBGene00002992 | Interactor_type | Effector | |
WBGene00023497 | Interactor_type | Affected | |||
WBGene00023498 | Interactor_type | Affected | |||
Variation_interactor | WBVar00089467 | Interactor_type | Effector | ||
WBVar00144287 | Interactor_type | Affected | |||
Interaction_summary | lin-15(e1763) mutant animals display a 54% penetrance of P11 to P12 fate transformation (Table 1A). However lin-15 acts in a signal dependent manner as loss of LIN-3 activity removes its effect on P11 and P12 cells. lin-3(n378/n1059) mutants do not display a P11/P12 defect (Table 2), neither do lin-3(n378/n1059); lin-15(e1763) double mutant animals (n=45). Therefore, lin-3(n378/n1059) suppresses the P11 to P12 fate transformation phenotype of lin-15(e1763) mutants. | ||||
Throughput | Low_throughput | ||||
Interaction_phenotype | WBPhenotype:0000414 | ||||
WBProcess | WBbiopr:00000024 | ||||
Paper | WBPaper00003135 | ||||
Remark | Data not shown |