WormBase Tree Display for Interaction: WBInteraction000524532
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| WBInteraction000524532 | Interaction_type | Genetic | Enhancement | ||
|---|---|---|---|---|---|
| GI_module_two | Enhancing | ||||
| Interactor | Interactor_overlapping_gene | WBGene00019126 | Interactor_type | Effector | |
| WBGene00006831 | Interactor_type | Affected | |||
| Variation_interactor | WBVar02125688 | Interactor_type | Effector | ||
| WBVar02141295 | Interactor_type | Affected | |||
| Interaction_summary | Authors observed that synaptic vesicle (SV) soma accumulations are further increased in the sam-4 unc- 104(js901) double mutant relative to either single mutant. Additionally, we found that sam-4 unc-104(js901) double mutants exhibit very severe locomotion defects relative to either single mutant, exhibiting defects comparable to severe unc-104 mutants. These results suggest that SAM-4 functions in concert with the UNC-104 protein to regulate the SV trafficking. | ||||
| Throughput | Low_throughput | ||||
| Interaction_phenotype | WBPhenotype:0000643 | ||||
| WBProcess | WBbiopr:00000047 | ||||
| Paper | WBPaper00045884 |
