WormBase Tree Display for Interaction: WBInteraction000536772
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| WBInteraction000536772 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00002008 | Interactor_type | Trans_regulated | |
| Transgene | WBTransgene00005180 | ||||
| WBGene00004879 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00249875 | Interactor_type | Trans_regulator | ||
| Interaction_summary | "To assess whether ER protein-folding homeostasis requires NMD-mediated mRNA surveillance, we analyzed deletions of the NMD genes smg-1, smg-4, and smg-6 in the zcIs4 transgenic hsp-4 GFP reporter strain. All strains displayed greater GFP fluorescence compared the parental zcIs4 strain (Fig. 2A and Fig. S6), and qRT-PCR revealed that the expression of endogenous hsp-4 mRNA was constitutively elevated in the smg-1(tm849) and smg-6(ok1794) mutant strains compared the wild type N2 (Fig. 2B)." | ||||
| Detection_method | Reporter_gene | Phsp-4::GFP | |||
| Transgene | |||||
| RT_PCR | |||||
| Regulation_level | Transcriptional | ||||
| Paper | WBPaper00041065 | ||||
| Remark | Figure 2B |
