WormBase Tree Display for Interaction: WBInteraction000541213
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| WBInteraction000541213 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00001898 | Interactor_type | Trans_regulated | |
| Transgene | WBTransgene00015882 | ||||
| Construct | WBCnstr00015453 | ||||
| Other_interactor | Bacillus thuringiensis infection | Interactor_type | Trans_regulator | ||
| Interaction_summary | "Following infection, in 45% of worms (n = 120) HIS-24::GFP was found to be present in both the nucleus and cytoplasm as well as in the cytosol (20% of 120 infected worms) (Fig. 7B and C). The observed changes in cellular localization depend on HIS-24 methylation since the subcellular localization of HIS- 24K14A::GFP was unaltered upon infection (Fig. 7D and E)... We found that B. thuringiensis infection enhances considerably the formation of monomethylated histone HIS-24 (2-fold after 12 h and 4-fold after 24 h), whereas infection with the nonpathogenic strain of B. thuringiensis (DSM-350) had almost no effect (Fig. 7G and H). Therefore, bacterial infection strongly influences linker histone methylation." | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [his-24::gfp] | ||||
| Transgene | |||||
| Regulation_level | Post_translational | ||||
| Regulation_result | Positive_regulate | Anatomy_term | WBbt:0005792 | ||
| Subcellular_localization | cytoplasm | ||||
| Paper | WBPaper00040410 | ||||
| Remark | Fig. 7bc |
