WormBase Tree Display for Interaction: WBInteraction000557082
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| WBInteraction000557082 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00001978 | Interactor_type | Trans_regulated | |
| Transgene | WBTransgene00006387 | ||||
| Construct | WBCnstr00006235 | ||||
| WBGene00001006 | Interactor_type | Trans_regulator | |||
| Interaction_summary | "dlg-1(RNAi) embryos consistently show an AJM-1 mislocalization pattern that is distinct from that in let-413(RNAi) embryos: AJM-1 localizes to apical junctions, but unlike the even, uninterrupted AJM-1 pattern of wild-type embryos, we observe regions of AJM-1 aggregation that alternate with large regions in which AJM-1 expression is greatly reduced; this pattern is reminiscent of 'beads on a string' (Fig. 5a, h, h'). The HMP-1-GFP pattern in these embryos is unaltered, and AJM-1 remains closely adjacent to HMP-1-GFP at apical junctions (Fig. 5i, j)." | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [HMP-1::GFP] | ||||
| Transgene | |||||
| Regulation_level | Post_translational | ||||
| Regulation_result | Does_not_regulate | Life_stage | WBls:0000003 | ||
| Subcellular_localization | apical junctions | ||||
| Paper | WBPaper00004961 |
