WormBase Tree Display for Interaction: WBInteraction000557635
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WBInteraction000557635 | Interaction_type | Regulatory | Change_of_expression_level | ||
---|---|---|---|---|---|
Interactor | Interactor_overlapping_gene | WBGene00023497 | Interactor_type | Trans_regulator | |
WBGene00001250 | Interactor_type | Trans_regulated | |||
Variation_interactor | WBVar00089463 | Interactor_type | Trans_regulator | ||
Interaction_summary | "in double inactivation experiments, cooperation was observed between lin-15B and llin-35 Rb, rather than lin-15B and cki-1,2 Cip/Kip (Figure 2D; data not shown). Loss of either lin-15B or lin-35 alone did not cause additional cell division, while lin-35; lin-15B double RNAi resulted in supernumerary cell divisions, n = 10 animals)... we used the strong or complete loss-of-function alleles lin-35(n745) and lin-15B(n374) and obtained similar results (Figure 2D)." | ||||
Detection_method | Reporter_gene | [elt-2::GFP] | |||
Regulation_result | Negative_regulate | Anatomy_term | WBbt:0005772 | ||
Paper | WBPaper00005298 | ||||
Remark | Fig. 2d |