WormBase Tree Display for Expression_cluster: WBPaper00027758:Group_IV

WBPaper00027758:Group_IV Description: Genes with significantly increased expression levels only in the lin-35 mutant relative to controls.
  Species: Caenorhabditis elegans
  Algorithm: For each set of mutant data, the repeats were averaged, and a Z test [Z=(observedexpected)\/SE] was performed in Excel. A moderate correction for multiple testing (~17,600 genes) was performed by multiplying the calculated P-value by 10,000. After this correction, all genes with up- or downregulation greater than twofold, P<0.05 in any given mutant were selected. The hypergeometric probability test was used to calculate the significance of overlap of gene groups. Authors determined whether transcripts of Group I-IV genes are bound by GLD-1, based on a minimum criteria of >1.5 enrichment in GLD-1 immunoprecipitated samples compared to control immunoprecipitations (P < 0.01).
  Reference: WBPaper00027758
  Microarray_results (87)
  Gene (94)
  Attribute_of: Microarray_experiment: WBPaper00027758:efl-1(n3639)_vs_N2_1
      WBPaper00027758:efl-1(n3639)_vs_N2_2
      WBPaper00027758:efl-1(n3639)_vs_N2_3
      WBPaper00027758:efl-1(n3639)_vs_N2_4
      WBPaper00027758:dpl-1(n3316)_unc-4(e120)_vs_unc-4(e120)_1
      WBPaper00027758:dpl-1(n3316)_unc-4(e120)_vs_unc-4(e120)_2
      WBPaper00027758:dpl-1(n3316)_unc-4(e120)_vs_unc-4(e120)_3
      WBPaper00027758:lin-35(n745)_vs_N2_1
      WBPaper00027758:lin-35(n745)_vs_N2_2
      WBPaper00027758:lin-35(n745)_vs_N2_3
  Regulation: Regulated_by_gene: WBGene00003020
  Associated_with: Life_stage: WBls:0000057