WormBase Tree Display for Picture: WBPicture0000007366

WBPicture0000007366 Description: Figure 2. MAGI-1 is localized to adherens junctions and synapses. (A) As detected by fluorescence immunohistochemistry, MAGI-1 (red) co-localizes with DLG-1 (green) in a sub-set of hypodermal tissue (top) and intestine (bottom) during development. Shown in tadpole stage embryos. (B) MAGI-1 persists in a subset of epidermal tissues, including the hypodermal seam cells, the intestine (not shown), and the anus throughout development. An early larval stage is shown, anterior to the left, ventral side down. MAGI-1 is also localized to junctions in the developing and fully formed vulva (ventral aspect). (C) MAGI-1 and GLR-1::GFP were detected by fluorescence immunohistochemistry. Lateral view of the head showing MAGI-1 (red) labeling GLR-1::GFP-expressing cells (green). Anterior is left and dorsal is up. MAGI-1 was detected in the neurons AVA, AVD, and SMD (indicated by white arrows), as well as RMD and RMDV (not shown). (D) GFP and mRFP fluorescence detected in live animals. Ventral view of interneurons expressing GLR-1::GFP (green) and a C-terminal mRFP fusion (red) to either the short (MAGI-1S, top panels) or long (MAGI-1L, bottom panels) isoform of MAGI-1 (expressed from the glr-1 promoter). Anterior is to the left. Bars, 5 um.
  Name: journal.pone.0004613.g002.jpg
  Depict: Expr_pattern: Expr8581
    Anatomy: WBbt:0005300
      WBbt:0005353
      WBbt:0005364
      WBbt:0005733
      WBbt:0005753
      WBbt:0005772
      WBbt:0005842
      WBbt:0006748
      WBbt:0006818
    Cellular_component: GO:0043005
  Acknowledgment: Template: Reprinted from <Journal_URL>, <Article_URL>. <Publisher_URL> <Publication_year>.
    Publication_year: 2009
    Article_URL: DOI id 10.1371/journal.pone.0004613
    Journal_URL: PLoSOne
    Publisher_URL: PLoS
  Reference: WBPaper00032939