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WBPicture0000008453DescriptionFigure 2. Mutations resulting in a symmetric, "two ASEL" phenotype (class I phenotype). (A) Expression patterns of gcy-7::gfp, lim-6::gfp, and gcy-5::gfp in wild-type, cog-1(ot28), and unc-37(e262) mutant backgrounds. Adult animals are shown. Both gcy-7::gfp and lim-6::gfp are derepressed in ASER in unc-37 and cog-1 backgrounds, whereas gcy-5::gfp expression is lost in ASER. Arrows denote the excretory gland cell that expresses lim-6::gfp. (B) Quantification of the effects of cog-1 and unc-37 on ASE asymmetry. Animals were scored as adults (with the exception of ot59, which, because of their lethality, were scored as L1s). Note that derepression of lim-6 in ASER is always followed by a concomitant loss of gcy-5 expression.
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AcknowledgmentTemplateWormBase wishes to thank <Journal_URL> for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Reprinted from <Journal_URL>, <Article_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL>.
Publication_year2003
Article_URLDOIid10.1101/gad.1117903
Journal_URLGenes&Development
Publisher_URLColdSpringHarborLabPress
ReferenceWBPaper00006052