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| WBPicture0000008825 | Description | Figure 3. STAM-1A is an early endosomal protein that localizes with RAB-5 and HGRS-1 in male-specific neurons. (A) Confocal micrographs of Ppkd-2::STAM-1A:: DsRed2 and Ppkd-2::HGRS-1::GFP double-labeled males. STAM-1A and HGRS-1 colocalize in cell bodies, the bases of cilia, and along RnB dendrites. Like STAM-1, HGRS-1 does not localize to the cilium proper. Arrows point to colocalization of STAM-1A and HGRS-1 at the ciliary base of CEM and R3B. (B) Confocal micrographs of Ppkd-2::STAM-1A::GFP and Ppkd-2::mRFP::RAB-5 double-labeled males. RAB-5 is an early endosomal marker (Sato et al., 2005). STAM-1A colocalizes with RAB-5 in the cell body and ciliary base. (C) Higher magnification images show that RAB-5 and STAM-1A collocate in CEM cell body. (D) Higher magnification fluorescence and DIC/fluorescence images of CEM cilia. RAB-5 and STAM-1A are never observed in the cilium proper. Scale bars, (A and B) 10 um, and (C and D) 5 um. | |||
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| Name | F3.large.jpg | ||||
| Depict | Expr_pattern | Expr8036 | |||
| Expr8037 | |||||
| Anatomy (23) | |||||
| Cellular_component | GO:0005929 | ||||
| GO:0043025 | |||||
| Acknowledgment | Template | WormBase thanks <Journal_URL> for permission to reproduce figures from this article <Article_URL>. Please note that this material may be protected by copyright. Reprinted from <Journal_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL>. | |||
| Publication_year | 2007 | ||||
| Article_URL | DOI | id | 10.1091/mbc.E07-03-0239 | ||
| Journal_URL | MolecularBiologyoftheCell | ||||
| Publisher_URL | TheAmericanSocietyForCellBiology | ||||
| Reference | WBPaper00030801 |
