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WBPicture0000009588DescriptionFigure 3. unc-115 Is Expressed in Neurons and Epidermis and Localizes to the Cell Cortex. In all panels, dorsal is up and anterior is to the left. All animals are wild-type.(A) A 1.5-fold embryo showing GFPS expression in neurons, epidermis, and epidermiblasts in the anterior, posterior, and ventral regions (arrowheads).(B) A late L1 larva showing GFPS expression in the entire nervous system, including all neurons in the head and tail (arrows) and along the ventral cord (arrowheads).(C-E) Micrographs of animals harboring a functional GFPFL transgene. (C) A left ventral-lateral confocal image of neurons and processes near the left posterior lateral ganglion of an adult animal is shown. The cell bodies of PVM, SDQL, PVDL, and PDEL are labeled. Note exclusion of UNC-115::GFP from nuclei. Axons and axon fascicles are labeled: left (L) and right (R) fascicles of the ventral cord; a commissural process of a ventral cord motor neuron (C); the left sublateral nerves (SLN); and the canal-associated nerve (CAN). (D) UNC-115::GFP expression in the excretory canal of an adult animal. UNC-115::GFP accumulates in plaques (arrowheads) approximately 0.3 μm wide that form two rows down the cortex of the excretory canal. (E) UNC-115::GFP in the epidermal syncytium of a newly hatched L1 larva. UNC-115::GFP accumulates in plaques at the cortex of the syncytium (arrows) that are 1-3 μm in width. The lateral epidermal seam cells, which do not express UNC-115::GFP, are labeled V1-V6. The pharynx shows strong expression of UNC-115::GFP.
NameF3.jpg
DepictExpr_patternExpr1396
AnatomyWBbt:0003679
WBbt:0003681
WBbt:0004086
WBbt:0004090
WBbt:0004383
WBbt:0004993
WBbt:0005733
WBbt:0005812
WBbt:0006827
Cellular_componentGO:0005938
GO:0030424
GO:0043005
GO:0043025
AcknowledgmentTemplateReprinted from <Journal_URL>, <Article_URL>, Copyright <Publication_year>, with permission from <Publisher_URL>.
Publication_year1998
Article_URLDOIid10.1016/S0896-6273(00)80547-4
Journal_URLNeuron
Publisher_URLElsevier
ReferenceWBPaper00003196