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| WBPicture0000009793 | Description | Figure 5. Subcellular Localization of GFP-Tagged Full-Length, MOTOR, and C-TERMinal Domains of KLP-6. Confocal fluorescent images of cDNA KLP-6::GFP (A-C), C-TERM::GFP (D-F), and MOTOR::GFP (G-I) in male head (A, D, and G) and tail (C, F, and I). Cilia and axons are indicated by thin arrows and closed arrowheads, respectively. In (C), (F), and (I), the dashed box around the hook structure indicates HOB cilium.(A-C) KLP-6::GFP is distributed in a web-like pattern throughout neurons, including cilia. (B) Cilia of IL2 and CEM neurons shown at high magnification.(D-F) C-TERM::GFP is highly enriched in cilia of IL2s and CEMs and (F) RnBs and HOB. (D and F) Nuclear localization of C-TERM::GFP is also observed.(G-I) MOTOR::GFP is preferentially targeted to cell bodies and axons and is largely missing from cilia. (H) High magnification of IL2 and CEM cell bodies and axons from (G). Anterior-posterior (a-p) axis is indicated. Open arrows indicate filamentous, cage-like structures around IL2 cell bodies labeled by MOTOR::GFP. The scale bars represent 5 μm. | |||
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| Name | F5.jpg | ||||
| Depict | Expr_pattern | Expr9657 | |||
| Cellular_component | GO:0005634 | ||||
| GO:0005929 | |||||
| GO:0030424 | |||||
| GO:0043025 | |||||
| Acknowledgment | Template | Reprinted from <Journal_URL>, <Article_URL>, Copyright <Publication_year>, with permission from <Publisher_URL>. | |||
| Publication_year | 2005 | ||||
| Article_URL | DOI | id | 10.1016/j.cub.2004.12.073 | ||
| Journal_URL | CurrentBiology | ||||
| Publisher_URL | Elsevier | ||||
| Reference | WBPaper00025021 |
