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WBPicture0000013942 | Description | Fig 1. daf-41/ZC395.10 regulates dauer formation and stress resistance. (A) An alignment of protein sequences between C. elegans DAF-41, D. melanogaster CG16817 and Homo sapiens p23/PTGES3. The similarity between DAF-41 and p23/PTGES3 is 44.6 percent. (B) Schematic illustration of the daf41, and deletion alleles of ok3015 and ok3052. Black arrows indicate the direction of transcription. Red area indicates HSP20-like co-chaperone domain. (C) daf-41 mutants constitutively formed dauer larvae (Daf-c) weakly at 25 degrees C and strongly at 27 degrees C. (D) Dauer alae of daf-41(ok3052) animals grown at 27 degrees C are indicated by the white arrows. (E) daf-41(ok3052) worms were resistant for oxidative stress (20uM of H2O2, 2.5 hrs) and heat stress (35 degrees C, 8 hrs). gst-4 (ok2358) worms were also slightly stress tolerant. (F) daf-41p::gfp (i.e. dpy-5(e907); sEx10796 [rCes daf-41::gfp + pCeh361]) worms were labeled with DiI and photos taken at the young adult stage. Patterns of gene expression of daf-41p::gfp (green), DiI (red), and merged figures are shown, with arrows indicating individual neurons. | |||
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Name | FigE.jpg | ||||
Crop | Crop_picture | WBPicture0000013943 | |||
Acknowledgment | Template | Reprinted from <Journal_URL>, <Article_URL>. <Publisher_URL> <Publication_year>. | |||
Publication_year | 2015 | ||||
Article_URL | DOI | id | 10.1371/journal.pgen.1005023 | ||
Journal_URL | PLoSGenetics | ||||
Publisher_URL | PLoS | ||||
Reference | WBPaper00046600 |