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WormBase Tree Display for RNAi: WBRNAi00090777

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Name Class

WBRNAi00090777HomolHomol_homolH13N06:RNAi
Sequence_infoPCR_productsjj_H13N06.3
ExperimentLaboratoryMZE
Date19 Apr 2012 00:00:00
Genotypeunc-119(ed3) III; cbgIs91[pPept-1:pept-1::DsRed;unc-119(+)]; cbgIs98[pPept-1:GFP::rab-11.1;unc-119(+)]
TreatmentAnimals were fed dsRNA-expressing bacteria from the L1 stage of the P0 generation; F1 young adult animals were imaged and scored for phenotypes
Delivered_byBacterial_feeding
InhibitsPredicted_geneH13N06.3Inferred_automaticallyRNAi_primary
GeneWBGene00001649Inferred_automaticallyRNAi_primary
TranscriptH13N06.3.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
ReferenceWBPaper00041129
PhenotypeWBPhenotype:0000679RemarkGFP::RAB-11 recycling endosome (RE) morphology appears diffuse or GFP::RAB-11 is cytosolically distributed; GFP::RAB-11 recycling endosomes (REs) enrich apically, but with a different morphology or distribution than in wild type; GFP::RAB-11 fluorescence intensity reduced; Autofluorescent lysosome-related organelles (AF/LROs) are enlarged or accumulated; Autofluorescent lysosome-related organelles (AF/LROs) appear diffuse; Autofluorescent lysosome-related organelles (AF/LROs) material is extracellulary, in the gut lumen
WBPhenotype:0001278RemarkGFP::RAB-11 recycling endosome (RE) morphology appears diffuse or GFP::RAB-11 is cytosolically distributed; GFP::RAB-11 recycling endosomes (REs) enrich apically, but with a different morphology or distribution than in wild type; GFP::RAB-11 fluorescence intensity reduced; Autofluorescent lysosome-related organelles (AF/LROs) are enlarged or accumulated; Autofluorescent lysosome-related organelles (AF/LROs) appear diffuse; Autofluorescent lysosome-related organelles (AF/LROs) material is extracellulary, in the gut lumen
WBPhenotype:0002094RemarkGFP::RAB-11 recycling endosome (RE) morphology appears diffuse or GFP::RAB-11 is cytosolically distributed; GFP::RAB-11 recycling endosomes (REs) enrich apically, but with a different morphology or distribution than in wild type; GFP::RAB-11 fluorescence intensity reduced; Autofluorescent lysosome-related organelles (AF/LROs) are enlarged or accumulated; Autofluorescent lysosome-related organelles (AF/LROs) appear diffuse; Autofluorescent lysosome-related organelles (AF/LROs) material is extracellulary, in the gut lumen
WBPhenotype:0002095RemarkGFP::RAB-11 recycling endosome (RE) morphology appears diffuse or GFP::RAB-11 is cytosolically distributed; GFP::RAB-11 recycling endosomes (REs) enrich apically, but with a different morphology or distribution than in wild type; GFP::RAB-11 fluorescence intensity reduced; Autofluorescent lysosome-related organelles (AF/LROs) are enlarged or accumulated; Autofluorescent lysosome-related organelles (AF/LROs) appear diffuse; Autofluorescent lysosome-related organelles (AF/LROs) material is extracellulary, in the gut lumen
WBPhenotype:0002099RemarkGFP::RAB-11 recycling endosome (RE) morphology appears diffuse or GFP::RAB-11 is cytosolically distributed; GFP::RAB-11 recycling endosomes (REs) enrich apically, but with a different morphology or distribution than in wild type; GFP::RAB-11 fluorescence intensity reduced; Autofluorescent lysosome-related organelles (AF/LROs) are enlarged or accumulated; Autofluorescent lysosome-related organelles (AF/LROs) appear diffuse; Autofluorescent lysosome-related organelles (AF/LROs) material is extracellulary, in the gut lumen
Remark(Table S1) H13N06.3/gob-1 RNAi
MethodRNAi