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WormBase Tree Display for RNAi: WBRNAi00098017

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Name Class

WBRNAi00098017HomolHomol_homolB0025:RNAi
Sequence_infoPCR_productsjj_B0025.1
ExperimentLaboratoryWS
Date02 Mar 2011 00:00:00
Genotypegla-3(op216); LST-4c::YFP
Temperature20
Delivered_byBacterial_feeding
InhibitsPredicted_geneB0025.1cInferred_automaticallyRNAi_primary
B0025.1aInferred_automaticallyRNAi_primary
GeneWBGene00006932Inferred_automaticallyRNAi_primary
TranscriptB0025.1c.1Inferred_automaticallyRNAi_primary
B0025.1a.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
ReferenceWBPaper00038320
PhenotypeWBPhenotype:0000306RemarkRecruitment of LST-4c::YFP to phagosomes containing germ cell corpses was greatly diminished in vps-34(RNAi) animals, suggesting that VPS-34 is required for efficient recruitment or maintenance of LST-4 on early phagosome membranes.
RemarkExact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation. gla-3 mutants used in this experiment as they have an increased number of apoptotic germ cells.
MethodRNAi