WormBase Tree Display for Strain: WBStrain00026463
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| WBStrain00026463 | Status | Live | ||
|---|---|---|---|---|
| Genotype | mei-1(ct46) unc-13(e1091) I; unc-119(ed3) III; abcIs3. | |||
| Public_name | MAS94 | |||
| Contains | Gene | WBGene00003183 | ||
| WBGene00006752 | ||||
| WBGene00006843 | ||||
| Variation | WBVar00054417 | |||
| WBVar00143733 | ||||
| WBVar00145093 | ||||
| Transgene | WBTransgene00018947 | |||
| Properties | Outcrossed | x0 | ||
| Mutagen | Microparticle bombardment | |||
| CGC_received | 27 Mar 2014 00:00:00 | |||
| Location | CGC | |||
| Made_by | WBPerson14050 | |||
| Remark | abcIs3 [pie-1p::ebp-2::GFP + unc-119(+)]. Embryonic-lethal at 25C due to dominant gain-of-function mutation mei-1(ct46), and Uncoordinated due to unc-13 mutation. Maternal expression of EBP-2::GFP microtubule end-binding protein. EBP-2 encodes an EB1-like protein (end-binding) that, in early embryos, locates to the growing tips of microtubules. A strong fluorescent signal localizes to the centrosomes of early embryos due to a high concentration of polymerizing microtubules. mei-1(ct46)-based ectopic microtubule severing causes mitotic spindle defects in the early embryo. References: Gusnowski EM, Srayko M. J Cell Biol. 2011 Aug 8;194(3):377-86. Tegha-Dunghu J, et al. Methods Mol Biol. 2014;1136:103-16. | Inferred_automatically | From CGC strain data | |
| Species | Caenorhabditis elegans |
