WormBase Tree Display for Strain: WBStrain00035068
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| WBStrain00035068 | Status | Live | ||
|---|---|---|---|---|
| Genotype | oma-1(zu405te33)/nT1 [unc-?(n754) let-?] IV; oma-2(te51)/nT1 V. | |||
| Public_name | TX183 | |||
| Contains | Gene | WBGene00003864 | ||
| WBGene00003865 | ||||
| Variation | WBVar00089727 | |||
| WBVar00275548 | ||||
| WBVar00249258 | ||||
| WBVar00249253 | ||||
| Rearrangement | nT1 | |||
| nT1[unc-?(n754dm) let-?] | ||||
| Properties | Outcrossed | x6 | ||
| CGC_received | 20 Dec 2002 00:00:00 | |||
| Location | CGC | |||
| Made_by | WBPerson374 | |||
| Remark | Heterozygotes are Unc and segregate Unc and non-Unc steriles (oma-1; oma-2 homozygotes). The Oma animal has an empty uterus and lots of oocytes in the gonad arms. Maintain by picking Uncs. zu405 is a gain-of-function mutation which results in temperature sensitive, embryonic lethality. Loss-of-function mutation in either oma-1 or oma-2 alone does not have a detectable phenotype. te33 is a dominant suppressor of the zu405 embryonic lethality. te51 is a mutation that, in the oma-1(zu405te33) background, gives an Oma (Ooctye Maturation defective) phenotype. | Inferred_automatically | From CGC strain data | |
| Heterozygotes are Unc and segregate Unc and non-Unc steriles (oma-1; oma-2 homozygotes). The Oma animal has an empty uterus and lots of oocytes in the gonad arms. Maintain by picking Uncs. zu405 is a gain-of-function mutation which results in temperature sensitive, embryonic lethality. Loss-of-function mutation in either oma-1 or oma-2 alone does not have a detectable phenotype. te33 is a dominant suppressor of the zu405 embryonic lethality. te51 is a mutation that, in the oma-1(zu405te33) background, gives an Oma (Ooctye Maturation defective) phenotype. [NOTE (09/2016; D. Greenstein, unpublished results): The two molecular changes in te33 are different than reported by Detwiler et al. (2001), but nonetheless result in a strong loss of oma-1 function. Sequencing of the original isolate of te33 gave the same result (S. Robertson and R. Lin, unpublished results).] This strain carrying oma-1(zu405te33) contains the following mutations: zu405 [C8889984T; P240L] and te33 [C8889978A, S238stop & C8889863T, H200Y]. | Inferred_automatically | From CGC strain data | ||
| Species | Caenorhabditis elegans |
