WormBase Tree Display for Strain: WBStrain00040935
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WBStrain00040935 | Status | Live | |||||||
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Genotype | C. briggsae wild isolate. | ||||||||
Public_name | AF16 | ||||||||
Contains | Variation | WBVar00249046 | |||||||
Properties | CGC_received | 01 Feb 1982 00:00:00 | |||||||
Phenotype | WBPhenotype:0000147 | Paper_evidence | WBPaper00059614 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Adults displayed a modest but statistically insignificant decrease in post-dauer brood size compared to control adults, unlike N2 animals. | Paper_evidence | WBPaper00059614 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001171 | Paper_evidence | WBPaper00058993 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | -GPA does not extend lifespan at the concentrations tested; in fact, in only one instance was an effect detected and, in that case, the compound reduced lifespan (Fig. 1). This conclusion is based on one biological replicate per concentration and, as such, could be considered preliminary. | Paper_evidence | WBPaper00058993 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Image | WBPicture0000014943 | Paper_evidence | WBPaper00058993 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Affected_by | Molecule | WBMol:00007871 | Paper_evidence | WBPaper00058993 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001420 | Paper_evidence | WBPaper00029153 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Animals are able to grow on lawns of Yersinia pseudotuberculosis. | Paper_evidence | WBPaper00029153 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001764 | Paper_evidence | WBPaper00031936 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Remark | Essentially unresponsive to CO2 compared to N2 control | Paper_evidence | WBPaper00031936 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
EQ_annotations | Life_stage | WBls:0000057 | PATO:0000460 | Paper_evidence | WBPaper00031936 | ||||
Curator_confirmed | WBPerson2021 | ||||||||
Phenotype_assay | Treatment | 10% CO2 | Paper_evidence | WBPaper00031936 | |||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0002140 | Paper_evidence | WBPaper00032050 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Unlike in C. elegans, males responded only weakly to a mixture of C. elegans ascr#2, ascr#3 and ascr#4 compared to a control compound. | Paper_evidence | WBPaper00032050 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Treatment | We tested 20 fmol ascr#2, 20 fmol ascr#3, and 1 pmol ascr#4 on the different species. | Paper_evidence | WBPaper00032050 | |||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_not_observed | WBPhenotype:0000039 | Paper_evidence | WBPaper00059661 | ||||||
WBPaper00061801 | |||||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Our results indicate that obeticholic acid does not have a consistent beneficial effect on lifespan in any of the C. elegans or C. briggsae strains tested at the concentrations used. This conclusion is based upon two biological replicates at each concentration performed in one lab, resulting in an average of 104 individuals measured per strain and concentration, and should be considered preliminary. | Paper_evidence | WBPaper00059661 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
"diuron does not exert robust positive effects on lifespan across three species of Caenorhabditis nematodes (Fig. 1)." Diuron does not have any significant effect on life span of AF16 across multiple concentrations. | Paper_evidence | WBPaper00061801 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Affected_by | Molecule | WBMol:00007887 | Paper_evidence | WBPaper00059661 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBMol:00003951 | Paper_evidence | WBPaper00061801 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000256 | Paper_evidence | WBPaper00032429 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Remark | The arrangement of amphid cell bodies (as seen in N2 animals) is conserved in this species. The position and size of the putative ASH neuron was similar to C. elegans. | Paper_evidence | WBPaper00032429 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0000663 | Paper_evidence | WBPaper00032429 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Remark | This species responded similarly to C. elegans with respect to response times to 2 M glycerol | Paper_evidence | WBPaper00032429 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0001452 | Paper_evidence | WBPaper00032429 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Remark | This species responded after ~2-3 seconds of octanol exposure, indicating that these species are similar in sensitivity to C. elegans. | Paper_evidence | WBPaper00032429 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
Affected_by | Molecule | WBMol:00001966 | Paper_evidence | WBPaper00032429 | |||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0001612 | Paper_evidence | WBPaper00035666 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Remark | C. briggsae does not differ significantly from C. elegans in its response to ethanol | Paper_evidence | WBPaper00035666 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0001871 | Paper_evidence | WBPaper00057026 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Imatinib mesylate does not extend lifespan in any of the Caenorhabditis species at the concentrations tested here; in fact, at some concentrations, this compound reduced nematode lifespan, although this effect was not consistent among species (Fig. 1) | Paper_evidence | WBPaper00057026 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Image | WBPicture0000014907 | Paper_evidence | WBPaper00057026 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0002212 | Paper_evidence | WBPaper00032429 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Remark | All amphid neurons showed relatively strong dye uptake | Paper_evidence | WBPaper00032429 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0004026 | Paper_evidence | WBPaper00032429 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Remark | Animals exhibited a nose touch response that was similar to that of C. elegans | Paper_evidence | WBPaper00032429 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
Location | CGC | ||||||||
AF | |||||||||
Made_by | WBPerson964 | ||||||||
Remark | See WBG 7(1) 48. Isolated from soil in Ahmedabad, India. Previously called C. briggsae G16. | Inferred_automatically | From CGC strain data | ||||||
Non-elegans Strain | |||||||||
Reference WBPaper00056884 added based on published strain data identified by Textpresso literature search. | |||||||||
Reference WBPaper00056998 added based on published strain data identified by Textpresso literature search. | |||||||||
Generated from papers flagged positive during the last month for data type afp_strain/other_strain. | |||||||||
WBStrain provided so WBPaper00059443 paper added based on AFP_Strain data. | Curator_confirmed | WBPerson1983 | |||||||
WBStrain mapped, WBPaper00061356 added based on AFP_Strain data. | Curator_confirmed | WBPerson1983 | |||||||
WBStrain mapped, WBPaper00060132 added based on AFP_Strain data. | Curator_confirmed | WBPerson1983 | |||||||
Reference (37) | |||||||||
Species | enorhabditis briggsae | ||||||||
Wild_isolate |