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WormBase Tree Display for Strain: WBStrain00040935

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Name Class

WBStrain00040935StatusLive
GenotypeC. briggsae wild isolate.
Public_nameAF16
ContainsVariationWBVar00249046
PropertiesCGC_received01 Feb 1982 00:00:00
PhenotypeWBPhenotype:0000147Paper_evidenceWBPaper00059614
Curator_confirmedWBPerson712
RemarkAdults displayed a modest but statistically insignificant decrease in post-dauer brood size compared to control adults, unlike N2 animals.Paper_evidenceWBPaper00059614
Curator_confirmedWBPerson712
WBPhenotype:0001171Paper_evidenceWBPaper00058993
Curator_confirmedWBPerson712
Remark-GPA does not extend lifespan at the concentrations tested; in fact, in only one instance was an effect detected and, in that case, the compound reduced lifespan (Fig. 1). This conclusion is based on one biological replicate per concentration and, as such, could be considered preliminary.Paper_evidenceWBPaper00058993
Curator_confirmedWBPerson712
ImageWBPicture0000014943Paper_evidenceWBPaper00058993
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00007871Paper_evidenceWBPaper00058993
Curator_confirmedWBPerson712
WBPhenotype:0001420Paper_evidenceWBPaper00029153
Curator_confirmedWBPerson712
RemarkAnimals are able to grow on lawns of Yersinia pseudotuberculosis.Paper_evidenceWBPaper00029153
Curator_confirmedWBPerson712
WBPhenotype:0001764Paper_evidenceWBPaper00031936
Curator_confirmedWBPerson2021
RemarkEssentially unresponsive to CO2 compared to N2 controlPaper_evidenceWBPaper00031936
Curator_confirmedWBPerson2021
EQ_annotationsLife_stageWBls:0000057PATO:0000460Paper_evidenceWBPaper00031936
Curator_confirmedWBPerson2021
Phenotype_assayTreatment10% CO2Paper_evidenceWBPaper00031936
Curator_confirmedWBPerson2021
WBPhenotype:0002140Paper_evidenceWBPaper00032050
Curator_confirmedWBPerson712
RemarkUnlike in C. elegans, males responded only weakly to a mixture of C. elegans ascr#2, ascr#3 and ascr#4 compared to a control compound.Paper_evidenceWBPaper00032050
Curator_confirmedWBPerson712
Phenotype_assayTreatmentWe tested 20 fmol ascr#2, 20 fmol ascr#3, and 1 pmol ascr#4 on the different species.Paper_evidenceWBPaper00032050
Curator_confirmedWBPerson712
Phenotype_not_observedWBPhenotype:0000039Paper_evidenceWBPaper00059661
WBPaper00061801
Curator_confirmedWBPerson712
RemarkOur results indicate that obeticholic acid does not have a consistent beneficial effect on lifespan in any of the C. elegans or C. briggsae strains tested at the concentrations used. This conclusion is based upon two biological replicates at each concentration performed in one lab, resulting in an average of 104 individuals measured per strain and concentration, and should be considered preliminary.Paper_evidenceWBPaper00059661
Curator_confirmedWBPerson712
"diuron does not exert robust positive effects on lifespan across three species of Caenorhabditis nematodes (Fig. 1)." Diuron does not have any significant effect on life span of AF16 across multiple concentrations.Paper_evidenceWBPaper00061801
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00007887Paper_evidenceWBPaper00059661
Curator_confirmedWBPerson712
WBMol:00003951Paper_evidenceWBPaper00061801
Curator_confirmedWBPerson712
WBPhenotype:0000256Paper_evidenceWBPaper00032429
Curator_confirmedWBPerson2021
RemarkThe arrangement of amphid cell bodies (as seen in N2 animals) is conserved in this species. The position and size of the putative ASH neuron was similar to C. elegans.Paper_evidenceWBPaper00032429
Curator_confirmedWBPerson2021
WBPhenotype:0000663Paper_evidenceWBPaper00032429
Curator_confirmedWBPerson2021
RemarkThis species responded similarly to C. elegans with respect to response times to 2 M glycerolPaper_evidenceWBPaper00032429
Curator_confirmedWBPerson2021
WBPhenotype:0001452Paper_evidenceWBPaper00032429
Curator_confirmedWBPerson2021
RemarkThis species responded after ~2-3 seconds of octanol exposure, indicating that these species are similar in sensitivity to C. elegans.Paper_evidenceWBPaper00032429
Curator_confirmedWBPerson2021
Affected_byMoleculeWBMol:00001966Paper_evidenceWBPaper00032429
Curator_confirmedWBPerson2021
WBPhenotype:0001612Paper_evidenceWBPaper00035666
Curator_confirmedWBPerson2021
RemarkC. briggsae does not differ significantly from C. elegans in its response to ethanolPaper_evidenceWBPaper00035666
Curator_confirmedWBPerson2021
WBPhenotype:0001871Paper_evidenceWBPaper00057026
Curator_confirmedWBPerson712
RemarkImatinib mesylate does not extend lifespan in any of the Caenorhabditis species at the concentrations tested here; in fact, at some concentrations, this compound reduced nematode lifespan, although this effect was not consistent among species (Fig. 1)Paper_evidenceWBPaper00057026
Curator_confirmedWBPerson712
ImageWBPicture0000014907Paper_evidenceWBPaper00057026
Curator_confirmedWBPerson712
WBPhenotype:0002212Paper_evidenceWBPaper00032429
Curator_confirmedWBPerson2021
RemarkAll amphid neurons showed relatively strong dye uptakePaper_evidenceWBPaper00032429
Curator_confirmedWBPerson2021
WBPhenotype:0004026Paper_evidenceWBPaper00032429
Curator_confirmedWBPerson2021
RemarkAnimals exhibited a nose touch response that was similar to that of C. elegansPaper_evidenceWBPaper00032429
Curator_confirmedWBPerson2021
LocationCGC
AF
Made_byWBPerson964
RemarkSee WBG 7(1) 48. Isolated from soil in Ahmedabad, India. Previously called C. briggsae G16.Inferred_automaticallyFrom CGC strain data
Non-elegans Strain
Reference WBPaper00056884 added based on published strain data identified by Textpresso literature search.
Reference WBPaper00056998 added based on published strain data identified by Textpresso literature search.
Generated from papers flagged positive during the last month for data type afp_strain/other_strain.
WBStrain provided so WBPaper00059443 paper added based on AFP_Strain data.Curator_confirmedWBPerson1983
WBStrain mapped, WBPaper00061356 added based on AFP_Strain data.Curator_confirmedWBPerson1983
WBStrain mapped, WBPaper00060132 added based on AFP_Strain data.Curator_confirmedWBPerson1983
Reference (37)
Speciesenorhabditis briggsae
Wild_isolate