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WormBase Tree Display for Transgene: WBTransgene00000524

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Name Class

WBTransgene00000524Public_namegaIs36
Summary[hs-mpk-1(+); EF1alpha-D-mek(gf); unc-30(+)]
ConstructionConstructWBCnstr00000523
Genetic_informationIntegrated
MapV
Map_evidencePaper_evidenceWBPaper00028398
PhenotypeWBPhenotype:0000099Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
RemarkThe gaIs36[hs-mpk-1(+); EF1a-D-mek(gf); unc-30(+)] transgene resulted in 26% of animals with the '0 P11.p' phenotype (P11 adopts a P12 fate). No animals exhibited the '2 P11.p' phenotype (P12 adopts a P11 fate).Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
PenetranceIncompletePaper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
Caused_by_geneWBGene00003401Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
EQ_annotationsAnatomy_termWBbt:0004410PATO:0000460Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
WBbt:0004409PATO:0000460Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
Phenotype_assayTreatmentgaIs36 strains were grown at 20 degrees Celsius and switched to 25 degrees Celsius (the temperature at which the gaIs36 strain is Muv) at the L4 stage because double-mutant strains were too sick to propagate at 25 degrees Celsius. Progeny of mothers grown at 20 degrees Celsius were scored at 25 degrees Celsius.Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
WBPhenotype:0000218Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
RemarkThe gaIs36[hs-mpk-1(+); EF1a-D-mek(gf); unc-30(+)] transgene resulted in more than the expected number of induced vulval precursor cells (3.69 on average instead of 3.0 in wild type)Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
Caused_by_geneWBGene00003401Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
EQ_annotationsAnatomy_termWBbt:0007809PATO:0000460Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
Phenotype_assayTreatmentgaIs36 strains were grown at 20 degrees Celsius and switched to 25 degrees Celsius (the temperature at which the gaIs36 strain is Muv) at the L4 stage because double-mutant strains were too sick to propagate at 25 degrees Celsius. Progeny of mothers grown at 20 degrees Celsius were scored at 25 degrees Celsius.Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
WBPhenotype:0000700Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
Remark53% of gaIs36[hs-mpk-1(+); EF1a-D-mek(gf); unc-30(+)] animals have multiple vulvaPaper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
PenetranceIncompletePaper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
Caused_by_geneWBGene00003401Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
EQ_annotationsAnatomy_termWBbt:0006748PATO:0000460Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
Phenotype_assayTreatmentgaIs36 strains were grown at 20 degrees Celsius and switched to 25 degrees Celsius (the temperature at which the gaIs36 strain is Muv) at the L4 stage because double-mutant strains were too sick to propagate at 25 degrees Celsius. Progeny of mothers grown at 20 degrees Celsius were scored at 25 degrees Celsius.Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
Phenotype_not_observedWBPhenotype:0000698Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
Caused_by_geneWBGene00003401Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
Phenotype_assayTreatmentgaIs36 strains were grown at 20 degrees Celsius and switched to 25 degrees Celsius (the temperature at which the gaIs36 strain is Muv) at the L4 stage because double-mutant strains were too sick to propagate at 25 degrees Celsius. Progeny of mothers grown at 20 degrees Celsius were scored at 25 degrees Celsius.Paper_evidenceWBPaper00005344
Curator_confirmedWBPerson2987
Used_forInteractorWBInteraction000002756
WBInteraction000002765
Reference (20)
SpeciesCaenorhabditis elegans