WormBase Tree Display for Transgene: WBTransgene00005164
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| WBTransgene00005164 | Public_name | ynIs79 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | [apl-1::APL-1-GFP] | ||||||||
| Synonym | APL-1::GFP | ||||||||
| Construction | Construct | WBCnstr00005141 | |||||||
| Construction_summary | According to WBPaper00029072, this transgene produce sAPL-1. | ||||||||
| Rescues apl-1 null lethality. | |||||||||
| Genetic_information | Integrated | ||||||||
| Map | V | ||||||||
| Phenotype | WBPhenotype:0000035 | Paper_evidence | WBPaper00029072 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | ynIs79 APL-1::GFP overexpression animals become translucent and large gaps are present between organs | Paper_evidence | WBPaper00029072 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Caused_by_gene | WBGene00000149 | Paper_evidence | WBPaper00029072 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000024 | PATO:0000460 | Paper_evidence | WBPaper00029072 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000154 | Paper_evidence | WBPaper00029072 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Transgenic strains overexpressing APL-1 have defects in brood size | Paper_evidence | WBPaper00029072 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Caused_by_gene | WBGene00000149 | Paper_evidence | WBPaper00029072 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000041 | PATO:0000460 | Paper_evidence | WBPaper00029072 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000273 | Paper_evidence | WBPaper00029072 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | All apl-1 transgenic overexpression strains showed a significantly reduced thrashing rate | Paper_evidence | WBPaper00029072 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Caused_by_gene | WBGene00000149 | Paper_evidence | WBPaper00029072 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000041 | PATO:0000460 | Paper_evidence | WBPaper00029072 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000603 | Paper_evidence | WBPaper00029072 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | In ynIs79 overexpression animals, muscle bundles are clearly separated from intestinal cells and the gonad | Paper_evidence | WBPaper00029072 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Caused_by_gene | WBGene00000149 | Paper_evidence | WBPaper00029072 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000024 | PATO:0000460 | Paper_evidence | WBPaper00029072 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0004018 | Paper_evidence | WBPaper00029072 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Overexpression animals had a decreased head bend rate compared with wild-type | Paper_evidence | WBPaper00029072 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Caused_by_gene | WBGene00000149 | Paper_evidence | WBPaper00029072 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000041 | PATO:0000460 | Paper_evidence | WBPaper00029072 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Reference | WBPaper00029072 | ||||||||
| WBPaper00031506 | |||||||||
| WBPaper00035550 | |||||||||
| WBPaper00037982 | |||||||||
| WBPaper00040923 | |||||||||
| WBPaper00041335 | |||||||||
| WBPaper00045780 | |||||||||
| WBPaper00050052 | |||||||||
| Species | Caenorhabditis elegans |
