WormBase Tree Display for Transgene: WBTransgene00005974
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WBTransgene00005974 | Public_name | bcEx801 | |||||
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Summary | [HS::mitogfp, HS::ced-9(wt)] | ||||||
Construction | Construct | WBCnstr00005838 | |||||
Genetic_information | Extrachromosomal | ||||||
Phenotype | WBPhenotype:0001401 | Paper_evidence | WBPaper00035144 | ||||
Curator_confirmed | WBPerson2021 | ||||||
Remark | A subpopulation of mitochondria of ced-9(wt)-overexpressing animals have increased thickness. Analysis of EM pictures revealed that the mitochondrial area is increased by 25% in transgenic lines overexpressing ced-9(wt) compared with control transgenic lines | Paper_evidence | WBPaper00035144 | ||||
Curator_confirmed | WBPerson2021 | ||||||
Caused_by_gene | WBGene00000423 | Paper_evidence | WBPaper00035144 | ||||
Curator_confirmed | WBPerson2021 | ||||||
WBPhenotype:0001402 | Paper_evidence | WBPaper00035144 | |||||
Curator_confirmed | WBPerson2021 | ||||||
Remark | The majority of embryos expressing ced-9(wt) had one or two highly globular mitochondria per cell | Paper_evidence | WBPaper00035144 | ||||
Curator_confirmed | WBPerson2021 | ||||||
Caused_by_gene | WBGene00000423 | Paper_evidence | WBPaper00035144 | ||||
Curator_confirmed | WBPerson2021 | ||||||
Phenotype_not_observed | WBPhenotype:0001400 | Paper_evidence | WBPaper00035144 | ||||
Curator_confirmed | WBPerson2021 | ||||||
Remark | No significant differences in the levels of bc1 protein, cytochrome oxidase I, and the alpha subunit of ATP synthase proteins were observed in transgenic lines overexpressing ced-9(wt) when compared to control | Paper_evidence | WBPaper00035144 | ||||
Curator_confirmed | WBPerson2021 | ||||||
Caused_by_gene | WBGene00000423 | Paper_evidence | WBPaper00035144 | ||||
Curator_confirmed | WBPerson2021 | ||||||
Reference | WBPaper00035144 | ||||||
Species | Caenorhabditis elegans |