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WormBase Tree Display for Transgene: WBTransgene00005975

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Name Class

WBTransgene00005975Public_namebcEx800
Summary[HS::mitogfp, HS::ced-9(wt)]
ConstructionConstructWBCnstr00005839
Genetic_informationExtrachromosomal
PhenotypeWBPhenotype:0001401Paper_evidenceWBPaper00035144
Curator_confirmedWBPerson2021
RemarkA subpopulation of mitochondria of ced-9(wt)-overexpressing animals have increased thickness. Analysis of EM pictures revealed that the mitochondrial area is increased by 25% in transgenic lines overexpressing ced-9(wt) compared with control transgenic linesPaper_evidenceWBPaper00035144
Curator_confirmedWBPerson2021
Caused_by_geneWBGene00000423Paper_evidenceWBPaper00035144
Curator_confirmedWBPerson2021
WBPhenotype:0001402Paper_evidenceWBPaper00035144
Curator_confirmedWBPerson2021
RemarkThe majority of embryos expressing ced-9(wt) had one or two highly globular mitochondria per cellPaper_evidenceWBPaper00035144
Curator_confirmedWBPerson2021
Caused_by_geneWBGene00000423Paper_evidenceWBPaper00035144
Curator_confirmedWBPerson2021
Phenotype_not_observedWBPhenotype:0001400Paper_evidenceWBPaper00035144
Curator_confirmedWBPerson2021
RemarkNo significant differences in the levels of bc1 protein, cytochrome oxidase I, and the alpha subunit of ATP synthase proteins were observed in transgenic lines overexpressing ced-9(wt) when compared to controlPaper_evidenceWBPaper00035144
Curator_confirmedWBPerson2021
Caused_by_geneWBGene00000423Paper_evidenceWBPaper00035144
Curator_confirmedWBPerson2021
ReferenceWBPaper00035144
SpeciesCaenorhabditis elegans