WormBase Tree Display for Rearrangement: hT3
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| hT3 | Name | Other_name | hT3(I;X) | |
|---|---|---|---|---|
| Variation | WBVar00146714 | |||
| Type | Translocation | |||
| Balances | I | From_left_end | ||
| Gene | WBGene00002583 | |||
| X | To_right_end | |||
| Gene | WBGene00001069 | |||
| Reference_strain | WBStrain00023948 | |||
| Remark | Summary: Translocation (rigorous proof of reciprocity lacking), moderately well characterized, very stable. Very effective balancer for left portion of LG I from left end to around let-363, and the right portion of LG X from the right end to between dpy-7 and unc-3. hT3(I), which disjoins from normal LG I, is probably LG X (right) translocated to LG I (right). hT3(X),which disjoins from normal LG X, is probably LG I (left) translocated to LG X (left). | Paper_evidence | WBPaper00029020 | |
| Growth characteristics: Original isolate marked with dpy-5 and unc-29. Homozygous inviable, probably breaks in let-363 (I). Heterozygotes exhibit reduced viability, low level of X chromosome nondisjunction (1.2%). | Paper_evidence | WBPaper00029020 | ||
| Handling: Easy to manipulate. Rare exceptional progeny carry one half-translocation as a free duplication. Recombination frequency in unbalanced intervals increased on both LG I and LG X. | Paper_evidence | WBPaper00029020 | ||
| Recommended use: General balancing, strain maintenance | ||||
| Isolation | Mutagen | Gamma irradiation mutagenesis of dpy-5(e61) unc-29(e403)/hT2[dpy-18(h662)] I; +/hT2[bli-4(e937)] III. Isolated as a lethal mutation balanced by hT2, now maintained as a homozygote balanced by szDp1. | ||
| Source_rearrangement | hT2 | |||
| Derived_rearrangement | hDp135 | |||
| hT3[dpy-5(e61)] | ||||
| Mapping_data | Pos_neg_data | 5033 | ||
| Strain | WBStrain00023947 |
