WormBase Tree Display for Expr_pattern: Expr4254
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| Expr4254 | Expression_of | Gene | WBGene00004035 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00004035 | ||
| Expression_data | Anatomy_term (21) | ||
| GO_term | GO:0030425 | ||
| GO:0030424 | |||
| GO:0005783 | |||
| GO:0043025 | |||
| Subcellular_localization | Each neuron that expresses PKD-2 has an exposed cilium at the distal ending of the dendrite. In these neurons, PKD-2::GFP localizes predominantly to cell bodies and cilia, and is also observed in small dendritic and axonal puncta. Within the ciliary region, PKD-2::GFP is distributed throughout the cilium, but primarily concentrated at the ciliary base, which corresponds to the distal-most dendrite and transition zone regions. | ||
| Type | Reporter_gene | [pkd-2::gfp] translational fusion. | |
| Pattern | pkd-2 is expressed in a subset of male-specific sensory neurons: four CEM neurons in the head, eight pairs of Ray B neurons (1-5 and 7-9, excluding R6B), and the HOB hook neuron in the tail. | ||
| Picture | WBPicture0000007716 | ||
| WBPicture0000007718 | |||
| WBPicture0000007720 | |||
| Remark | PKD-2::GFP transgenes fully rescue the male mating defect of pkd-2(sy606) null mutants. | ||
| Reference | WBPaper00028448 | ||
| Transgene | WBTransgene00001241 |
