WormBase Tree Display for Expr_pattern: Expr4260

Expr4260 Expression_of: Gene: WBGene00021910
    Reflects_endogenous_expression_of: WBGene00021910
  Expression_data: Anatomy_term: WBbt:0005117 Uncertain
      WBbt:0005319 Certain
      WBbt:0005394 Uncertain
      WBbt:0005772 Certain
      WBbt:0005828 Certain
      WBbt:0006784 Certain
    GO_term: GO:0005783
      GO:0016020
  Subcellular_localization: Intestinal STIM-1::GFP appeared to be localized to membrane and submembrane regions. Confocal Z-sections also revealed a prominent punctate localization in the anterior intestine and sheath cells. STIM-1::GFP expression showed a striking localization to a reticular structure in the posterior intestine. This reticular structure resembles the ER of C. elegans intestinal cells.
  Type: Reporter_gene
  Pattern: Prominent expression of STIM-1::GFP was detected in the spermatheca, gonad sheath cells, the intestine, and neurons in the head. Expression was also detected in uterine epithelial cells. STIM-1::GFP-expressing head neurons are likely amphid and/or inner labial (IL) neurons. Expression of STIM-1::GFP in the intestine was heterogeneous. The anterior and posterior intestine expressed the reporter very strongly while expression was weaker in the midsection.
  Picture: WBPicture0000011874
  Remark: More detailed studies are required to identify the cellular domains in which STIM-1::GFP is expressed. It should be noted here that the absence of detectable STIM-1::GFP expression in tissues other than those shown does not rule out a functional role for STIM-1 in other cell types. The 1.9-kb stim-1 promoter used in these studies may lack regulatory information required for cell-specific expression. In addition, STIM-1::GFP expression levels may be below detection levels in other tissues. More definitive identification of STIM-1 expression sites awaits the development of suitable antibodies for immunolocalization.
  Reference: WBPaper00028479
  Transgene: WBTransgene00012227