WormBase Tree Display for Gene: WBGene00004351

WBGene00004351 SMap: S_parent: Sequence: F52D2
  Identity: Version: 3
    Name: CGC_name: rgs-8.1 Person_evidence: WBPerson330
      Sequence_name: F52D2.2
      Molecular_name: F52D2.2
        F52D2.2.1
        CE04623
      Other_name: rgs-8
        CELE_F52D2.2 Accession_evidence: NDB BX284606
      Public_name: rgs-8.1
    DB_info: Database: AceView gene XC570
        WormQTL gene WBGene00004351
        WormFlux gene WBGene00004351
        NDB locus_tag CELE_F52D2.2
        Panther gene CAEEL|WormBase=WBGene00004351|UniProtKB=G5ECK9
          family PTHR10845
        NCBI gene 180507
        RefSeq protein NM_075958.3
        TrEMBL UniProtAcc G5ECK9
        UniProt_GCRP UniProtAcc G5ECK9
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:35 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 03 Dec 2004 16:50:34 WBPerson2970 Event: Acquires_merge: WBGene00018685
        3 10 Dec 2004 09:51:30 WBPerson2970 Name_change: CGC_name: rgs-8.1
      Acquires_merge: WBGene00018685
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: rgs
    Allele: WBVar00275075 Inferred_automatically: From strain object: LX543
      WBVar01499516
      WBVar02123550
      WBVar02121346
      WBVar01498608
      WBVar01498433
      WBVar01498815
      WBVar01499014
      WBVar01499751
      WBVar02123781
      WBVar01498292
      WBVar01498298
      WBVar01498308
      WBVar01498499
      WBVar01499424
      WBVar02123639
      WBVar02120881
      WBVar02122181
      WBVar01498338
      WBVar02121815
      WBVar01499636
      WBVar01498348
      WBVar01499086
      WBVar01500202
      WBVar01500203
      WBVar02120740
      WBVar01498563
      WBVar01498953
      WBVar01498593
    Strain: WBStrain00026365
    RNASeq_FPKM (74)
    Ortholog (15)
    Paralog: WBGene00004344 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00004347 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00004350 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00004352 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
      WBGene00021988 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
      WBGene00004353 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
      WBGene00004354 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
    Structured_description: Automated_description: Expressed in PVT and intestine. Human RGS1 enables G-protein alpha-subunit binding activity and GTPase activator activity. Is predicted to encode a protein with the following domains: RGS, subdomain 1/3; RGS domain; RGS domain superfamily; Regulator of G protein signaling domain; and RGS, subdomain 2. Is an ortholog of human RGS1 (regulator of G protein signaling 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F52D2.2
    Corresponding_transcript: F52D2.2.1
    Associated_feature: WBsf1004191
      WBsf1004192
      WBsf1004193
      WBsf1022385
      WBsf1022386
      WBsf237041
  Experimental_info: RNAi_result: WBRNAi00047969 Inferred_automatically: RNAi_primary
      WBRNAi00007546 Inferred_automatically: RNAi_primary
      WBRNAi00032610 Inferred_automatically: RNAi_primary
      WBRNAi00047970 Inferred_automatically: RNAi_primary
      WBRNAi00015401 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr14464
      Expr1014309
      Expr1151788
    Drives_construct: WBCnstr00035546
      WBCnstr00040892
    Construct_product: WBCnstr00035546
    Microarray_results: SMD_F52D2.2
      189970_s_at
      Aff_F52D2.2
    Expression_cluster: WBPaper00028788:MPK-1_Response_Strong
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00040285:H2S_24hr_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044760:germline_specific
      WBPaper00045521:Oogenic
      WBPaper00045774:clk-1_downregulated
      WBPaper00048971:daf-16(mgDf50)_downregulated_L1
      WBPaper00048988:neuron_expressed
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
      WBPaper00053368:F.oxysporum_regulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:daf-2(e1370)_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056167:Cry5B_upregulated
      WBPaper00059440:LAG-1_interacting_germline
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00060764:swsn-1(os22ts)_downregulated
      WBPaper00061274:hypergravity_15xg_upregulated
      WBPaper00061274:microgravity_upregulated
      WBPaper00061357:mett-10(ok2204)_upregulated_NA22
      WBPaper00061527:sea-1-R04D3.4
      WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated
      WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated
      WBPaper00061613:human-amyloid-beta_upregulated
      WBPaper00061753:csr-1(tor159)_downregulated_25C
      WBPaper00062446:nhr-8(hd117)_downregulated
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00064871:hypoxia_upregulated_F1
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065225:nhr-42(tm1375)_downregulated_S.aureus-infected
      WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
      WBPaper00065749:Heat-Shock_upregulated_N2
      cgc4386_cluster_6_1
      cgc4489_group_9
      WBPaper00025032:cluster_191
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00028948:cep-1(gk138)+UV_upregulated
      WBPaper00034739:N2lessDR1350
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00037611:RNP-8-associated
      WBPaper00037695:WC_5-day
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00039866:ClassComp_daf-19_downregulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00046083:oga-1(ok1207)_OP50_upregulated
      WBPaper00046083:ogt-1(ok1474)_OP50_upregulated
      WBPaper00046083:pmk-1(km25)_OP50_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo
      WBPaper00053550:daf-19(m86)_downregulated_AdultDay2
      [cgc5767]:cluster_88
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:Cluster_E
      [cgc6390]:intrinsic
    Interaction (58)
  Map_info: Map: X Position: -17.1822 Error: 0.016305
    Positive: Positive_clone: F52D2 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5027
        5037
    Pseudo_map_position
  Reference: WBPaper00004281
    WBPaper00053550
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene