WormBase Tree Display for Gene: WBGene00017464
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| WBGene00017464 | SMap | S_parent | Sequence | F14D12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | sulp-2 | Person_evidence | WBPerson2233 | |||||
| Sequence_name | F14D12.5 | ||||||||
| Molecular_name | F14D12.5 | ||||||||
| F14D12.5.1 | |||||||||
| CE27963 | |||||||||
| Other_name | CELE_F14D12.5 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | sulp-2 | ||||||||
| DB_info | Database | AceView | gene | XG216 | |||||
| WormQTL | gene | WBGene00017464 | |||||||
| WormFlux | gene | WBGene00017464 | |||||||
| NDB | locus_tag | CELE_F14D12.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00017464|UniProtKB=G5EDS5 | |||||||
| family | PTHR11814 | ||||||||
| NCBI | gene | 180828 | |||||||
| RefSeq | protein | NM_076543.7 | |||||||
| TrEMBL | UniProtAcc | G5EDS5 | |||||||
| UniProt_GCRP | UniProtAcc | G5EDS5 | |||||||
| OMIM | gene | 126650 | |||||||
| 604943 | |||||||||
| 605646 | |||||||||
| 610130 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:58 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 19 Jan 2005 16:30:54 | WBPerson2970 | Name_change | CGC_name | sulp-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sulp | ||||||||
| Allele | WBVar00092761 | Inferred_automatically | From strain object: RB1366 | ||||||
| WBVar00092764 | Inferred_automatically | From strain object: RB1369 | |||||||
| WBVar01468992 | |||||||||
| WBVar01468993 | |||||||||
| WBVar01879611 | |||||||||
| WBVar01879612 | |||||||||
| WBVar01468994 | |||||||||
| WBVar02050592 | |||||||||
| WBVar01879613 | |||||||||
| WBVar01468997 | |||||||||
| WBVar01879614 | |||||||||
| WBVar00504124 | |||||||||
| WBVar00504125 | |||||||||
| WBVar00504126 | |||||||||
| WBVar00504127 | |||||||||
| WBVar00504128 | |||||||||
| WBVar00504129 | |||||||||
| WBVar01819953 | |||||||||
| WBVar00079236 | |||||||||
| WBVar01148530 | |||||||||
| WBVar00079237 | |||||||||
| WBVar00079238 | |||||||||
| WBVar01148531 | |||||||||
| WBVar00079239 | |||||||||
| WBVar01148532 | |||||||||
| WBVar00079240 | |||||||||
| WBVar01148533 | |||||||||
| WBVar00079241 | |||||||||
| WBVar01148534 | |||||||||
| WBVar01148535 | |||||||||
| WBVar01148536 | |||||||||
| WBVar01148537 | |||||||||
| WBVar01148538 | |||||||||
| WBVar01148539 | |||||||||
| WBVar01148540 | |||||||||
| WBVar01148541 | |||||||||
| WBVar01148542 | |||||||||
| WBVar01148543 | |||||||||
| WBVar01148544 | |||||||||
| WBVar01148545 | |||||||||
| WBVar01148546 | |||||||||
| WBVar01148547 | |||||||||
| WBVar01148548 | |||||||||
| WBVar01148549 | |||||||||
| WBVar01148550 | |||||||||
| WBVar01148551 | |||||||||
| WBVar01830573 | |||||||||
| WBVar02063882 | |||||||||
| WBVar01549994 | |||||||||
| WBVar01500067 | |||||||||
| Strain | WBStrain00032065 | ||||||||
| WBStrain00032068 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Ortholog (44) | |||||||||
| Paralog | WBGene00010788 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00010789 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00012259 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00013963 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00016945 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00018283 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00020914 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | sulp-2 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-2 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids and when expressed in Xenopus oocytes, SULP-2 does exhibit modest uptake of sulfate; a SULP-2::GFP fusion is expressed in the intestine and rectal gland cells, where it localizes to the basolateral membrane and in cephalic and deirid neurons, where it localizes to sensillar endings. | Paper_evidence | WBPaper00025075 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 13 Sep 2006 00:00:00 | ||||||||
| Automated_description | Enables sulfate transmembrane transporter activity. Predicted to be involved in inorganic anion transmembrane transport and organic anion transport. Located in basolateral plasma membrane and non-motile cilium. Expressed in dopaminergic neurons and intestine. Human ortholog(s) of this gene implicated in several diseases, including Pendred Syndrome; autosomal recessive nonsyndromic deafness (multiple); and calcium oxalate nephrolithiasis. Is an ortholog of several human genes including SLC26A1 (solute carrier family 26 member 1); SLC26A3 (solute carrier family 26 member 3); and SLC26A4 (solute carrier family 26 member 4). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:12176 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8818) | ||||
| DOID:0060744 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8818) | ||||||
| DOID:0060296 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3018) | ||||||
| DOID:0110498 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8818) | ||||||
| DOID:0110513 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9359) | ||||||
| DOID:0080652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10993) | ||||||
| DOID:13250 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3018) | ||||||
| Molecular_info | Corresponding_CDS | F14D12.5 | |||||||
| Corresponding_transcript | F14D12.5.1 | ||||||||
| Other_sequence | CJC12795_1 | ||||||||
| Associated_feature | WBsf670538 | ||||||||
| WBsf237387 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00000992 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00030931 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00013264 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00044586 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3247 | ||||||||
| Expr3259 | |||||||||
| Expr1010356 | |||||||||
| Expr1148543 | |||||||||
| Expr2017113 | |||||||||
| Expr2035249 | |||||||||
| Drives_construct | WBCnstr00011250 | ||||||||
| WBCnstr00011262 | |||||||||
| WBCnstr00027278 | |||||||||
| Construct_product | WBCnstr00011262 | ||||||||
| WBCnstr00027278 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (152) | |||||||||
| Interaction (24) | |||||||||
| Map_info | Map | X | Position | -4.46315 | Error | 0.008938 | |||
| Positive | Positive_clone | F14D12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5231 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00025075 | ||||||||
| WBPaper00035539 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
