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WormBase Tree Display for Gene: WBGene00010789

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Name Class

WBGene00010789SMapS_parentSequenceK12G11
IdentityVersion2
NameCGC_namesulp-5Person_evidenceWBPerson2233
Sequence_nameK12G11.2
Molecular_nameK12G11.2
K12G11.2.1
CE52865
Other_nameCELE_K12G11.2Accession_evidenceNDBBX284605
Public_namesulp-5
DB_infoDatabaseAceViewgene5M363
WormQTLgeneWBGene00010789
WormFluxgeneWBGene00010789
NDBlocus_tagCELE_K12G11.2
PanthergeneCAEEL|WormBase=WBGene00010789|UniProtKB=O17951
familyPTHR11814
NCBIgene187335
RefSeqproteinNM_073589.5
TrEMBLUniProtAccO17951
UniProt_GCRPUniProtAccO17951
OMIMgene604943
608480
610130
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
219 Jan 2005 16:30:54WBPerson2970Name_changeCGC_namesulp-5
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsulp
Allele (33)
StrainWBStrain00031786
RNASeq_FPKM (74)
GO_annotation (19)
Ortholog (69)
ParalogWBGene00010788Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00013963Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00018283Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00012259Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00016945Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00017464Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00020914Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionsulp-5 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-5 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids; a SULP-5::GFP fusion is expressed in punctate structures irregularly distributed along the apical membrane of excretory cell canals and is also expressed weakly in adult seam cells.Paper_evidenceWBPaper00025075
Curator_confirmedWBPerson1843
Date_last_updated13 Sep 2006 00:00:00
Automated_descriptionPredicted to enable salt transmembrane transporter activity. Predicted to be involved in inorganic anion transmembrane transport and organic anion transport. Located in apical plasma membrane. Expressed in excretory canal and seam cell. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 61; calcium oxalate nephrolithiasis; and spermatogenic failure 3. Is an ortholog of human SLC26A5 (solute carrier family 26 member 5) and SLC26A6 (solute carrier family 26 member 6).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110513Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9359)
DOID:0070168Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:14468)
DOID:0080652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10993)
Molecular_infoCorresponding_CDSK12G11.2
Corresponding_CDS_historyK12G11.2:wp268
Corresponding_transcriptK12G11.2.1
Other_sequence (14)
Associated_featureWBsf216760
WBsf216761
WBsf216762
WBsf216763
WBsf216764
WBsf232564
WBsf232565
Experimental_infoRNAi_resultWBRNAi00050674Inferred_automaticallyRNAi_primary
WBRNAi00034317Inferred_automaticallyRNAi_primary
WBRNAi00017061Inferred_automaticallyRNAi_primary
Expr_patternExpr3250
Expr3257
Expr6397
Expr1017624
Expr1154383
Expr2017116
Expr2035252
Drives_constructWBCnstr00003325
WBCnstr00011253
WBCnstr00011260
WBCnstr00020374
WBCnstr00031143
WBCnstr00042017
WBCnstr00042018
WBCnstr00042019
WBCnstr00042020
Construct_productWBCnstr00011260
WBCnstr00031143
Microarray_results (21)
Expression_cluster (127)
Interaction (134)
Map_infoMapVPosition3.50423Error0.005915
PositivePositive_cloneK12G11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4408
5036
Pseudo_map_position
ReferenceWBPaper00025075
WBPaper00035475
WBPaper00035539
WBPaper00038491
WBPaper00055090
WBPaper00065265
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene