WormBase Tree Display for Gene: WBGene00018877
expand all nodes | collapse all nodes | view schema
WBGene00018877 | SMap | S_parent | Sequence | F55D10 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | aman-1 | Paper_evidence | WBPaper00027768 | |||||
Sequence_name | F55D10.1 | ||||||||
Molecular_name | F55D10.1 | ||||||||
F55D10.1.1 | |||||||||
CE28456 | |||||||||
Other_name | CELE_F55D10.1 | Accession_evidence | NDB | BX284606 | |||||
Public_name | aman-1 | ||||||||
DB_info | Database (13) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:31:00 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 05 Jan 2007 17:07:18 | WBPerson1847 | Name_change | CGC_name | aman-1 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | aman | ||||||||
Allele | WBVar00502076 | ||||||||
WBVar00502077 | |||||||||
WBVar01830256 | |||||||||
WBVar01830257 | |||||||||
WBVar00597643 | |||||||||
WBVar01830258 | |||||||||
WBVar01830259 | |||||||||
WBVar01830260 | |||||||||
WBVar01830261 | |||||||||
WBVar01495854 | |||||||||
WBVar01710747 | |||||||||
WBVar01710748 | |||||||||
WBVar01710749 | |||||||||
WBVar01710750 | |||||||||
WBVar01710751 | |||||||||
WBVar01710752 | |||||||||
WBVar01710753 | |||||||||
WBVar01710754 | |||||||||
WBVar01710755 | |||||||||
WBVar01710756 | |||||||||
WBVar01710757 | |||||||||
WBVar01819565 | |||||||||
WBVar01499756 | |||||||||
WBVar01499757 | |||||||||
WBVar00263245 | |||||||||
WBVar01678875 | |||||||||
WBVar01473754 | |||||||||
WBVar01980556 | |||||||||
WBVar01980557 | |||||||||
WBVar00604062 | |||||||||
WBVar01142497 | |||||||||
WBVar01142498 | |||||||||
WBVar01142499 | |||||||||
WBVar01142500 | |||||||||
WBVar01142501 | |||||||||
WBVar01142502 | |||||||||
WBVar02144425 | |||||||||
WBVar00078177 | |||||||||
WBVar01142503 | |||||||||
WBVar01142504 | |||||||||
WBVar00078178 | |||||||||
WBVar01142505 | |||||||||
WBVar00078179 | |||||||||
WBVar01142506 | |||||||||
WBVar01142507 | |||||||||
WBVar01142508 | |||||||||
WBVar01142509 | |||||||||
WBVar01142510 | |||||||||
WBVar01142511 | |||||||||
WBVar01142512 | |||||||||
WBVar01142513 | |||||||||
WBVar01142514 | |||||||||
WBVar01142515 | |||||||||
WBVar01498929 | |||||||||
WBVar01142516 | |||||||||
WBVar01142517 | |||||||||
WBVar01142518 | |||||||||
WBVar01142519 | |||||||||
WBVar01142520 | |||||||||
WBVar01142521 | |||||||||
WBVar01142522 | |||||||||
WBVar01142523 | |||||||||
WBVar01142524 | |||||||||
WBVar01142525 | |||||||||
WBVar01142526 | |||||||||
WBVar01142527 | |||||||||
WBVar01142528 | |||||||||
WBVar01142529 | |||||||||
WBVar01142530 | |||||||||
WBVar01142531 | |||||||||
WBVar01142532 | |||||||||
WBVar01142533 | |||||||||
WBVar01500236 | |||||||||
WBVar00502066 | |||||||||
WBVar00502067 | |||||||||
WBVar00502068 | |||||||||
WBVar00502069 | |||||||||
WBVar01878308 | |||||||||
WBVar00502070 | |||||||||
WBVar01878309 | |||||||||
WBVar00502071 | |||||||||
WBVar01878310 | |||||||||
WBVar00502072 | |||||||||
WBVar00502073 | |||||||||
WBVar00502074 | |||||||||
WBVar01500067 | |||||||||
WBVar00502075 | |||||||||
Strain | WBStrain00001773 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (11) | |||||||||
Ortholog (46) | |||||||||
Paralog | WBGene00010284 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00018594 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | aman-1 encodes an ortholog of human lysosomal mannosidase (MAN2B1;OMIM:609458, mutated in alpha-mannosidosis); AMAN-1 is predicted to helpdigest glycoproteins by removing mannose residues from their N-linkedoligosaccharides; AMAN-1 has seven predicted N-glycosylation sites;AMAN-1 is biochemically active in vitro, has optimal activity at pH4-4.5, and is unaffected by Co(II); however, AMAN-1 expressed in Pichiapastoris lacks normal activity, perhaps because it requires othersubunits in vivo; aman-1 is expressed in neurons and intestine. | Paper_evidence | WBPaper00006525 | |||||
WBPaper00027768 | |||||||||
Curator_confirmed | WBPerson1823 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 14 Mar 2007 00:00:00 | ||||||||
Automated_description | Predicted to enable alpha-mannosidase activity. Predicted to be involved in mannose metabolic process. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in alpha-mannosidosis. Is an ortholog of human MAN2B1 (mannosidase alpha class 2B member 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:3413 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6826) | ||||
Molecular_info | Corresponding_CDS | F55D10.1 | |||||||
Corresponding_transcript | F55D10.1.1 | ||||||||
Other_sequence (44) | |||||||||
Associated_feature | WBsf648039 | ||||||||
WBsf662713 | |||||||||
WBsf1005046 | |||||||||
WBsf1005047 | |||||||||
WBsf1005048 | |||||||||
WBsf1022842 | |||||||||
WBsf235625 | |||||||||
Experimental_info | RNAi_result | WBRNAi00015725 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00076484 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00048493 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00081081 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Chronogram257 | ||||||||
Expr6204 | |||||||||
Expr1011721 | |||||||||
Expr1038146 | |||||||||
Expr1152284 | |||||||||
Expr2009320 | |||||||||
Expr2027556 | |||||||||
Drives_construct | WBCnstr00002587 | ||||||||
WBCnstr00026220 | |||||||||
Construct_product | WBCnstr00009554 | ||||||||
WBCnstr00026220 | |||||||||
Microarray_results (20) | |||||||||
Expression_cluster (176) | |||||||||
Interaction | WBInteraction000049245 | ||||||||
WBInteraction000253230 | |||||||||
WBInteraction000371124 | |||||||||
WBInteraction000463533 | |||||||||
WBInteraction000573870 | |||||||||
Map_info | Map | X | Position | -6.75069 | |||||
Positive | Positive_clone | F55D10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00027768 | ||||||||
WBPaper00029024 | |||||||||
WBPaper00034662 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00055090 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |