WormBase Tree Display for Gene: WBGene00003575

WBGene00003575 Evidence: Author_evidence: Schwartz EM
  SMap: S_parent: Sequence: Y97E10B
  Identity: Version: 1
    Name: CGC_name: ncx-10
      Sequence_name: Y97E10B.7
      Molecular_name: Y97E10B.7a
        Y97E10B.7a.1
        CE26327
        Y97E10B.7b
        CE44502
        Y97E10B.7b.1
      Other_name: Y97E10B.b Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        Y97E10B.f Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        CELE_Y97E10B.7 Accession_evidence: NDB BX284605
      Public_name: ncx-10
    DB_info: Database: AceView gene 5I408
        WormQTL gene WBGene00003575
        WormFlux gene WBGene00003575
        NDB locus_tag CELE_Y97E10B.7
        Panther gene CAEEL|WormBase=WBGene00003575|UniProtKB=Q965R5
          family PTHR12266
        NCBI gene 190821
        RefSeq protein NM_001269165.1
            NM_001373058.1
        TREEFAM TREEFAM_ID TF323444
        TrEMBL UniProtAcc Q965R5
            D9P2J5
        UniProt_GCRP UniProtAcc Q965R5
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:32 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ncx
    Allele (36)
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog (44)
    Paralog: WBGene00003571 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00003572 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00003573 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00003574 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Concise_description: ncx-10 encodes a putative Na[+]/Ca[2+] exchanger of uncertain stoichiometry and affinity, orthologous to human SLC24A6 and paralogous to NCX-6/-9; NCX-10 may function intracellularly; NCX-10 has tandem Calx-alpha domains predicted to carry out ion transport; NCX-10 has no obvious function in mass RNAi assays. Paper_evidence: WBPaper00012774
            WBPaper00028596
            WBPaper00031156
            WBPaper00031157
            WBPaper00031158
            WBPaper00031159
            WBPaper00031160
          Curator_confirmed: WBPerson567
          Date_last_updated: 07 Nov 2007 00:00:00
      Automated_description: Predicted to enable calcium:sodium antiporter activity. Predicted to be involved in intracellular calcium ion homeostasis and monoatomic cation transport. Predicted to be located in membrane. Expressed in pharyngeal muscle cell and terminal bulb. Is an ortholog of human SLC8B1 (solute carrier family 8 member B1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y97E10B.7a
      Y97E10B.7b
    Corresponding_transcript: Y97E10B.7a.1
      Y97E10B.7b.1
    Associated_feature: WBsf234004
  Experimental_info: RNAi_result: WBRNAi00058691 Inferred_automatically: RNAi_primary
      WBRNAi00021541 Inferred_automatically: RNAi_primary
      WBRNAi00021542 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr11164
      Expr1028309
      Expr1162111
      Expr2013917
      Expr2032157
    Drives_construct: WBCnstr00018024
      WBCnstr00036030
    Construct_product: WBCnstr00036030
    Microarray_results (21)
    Expression_cluster: WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00038061:aldicarb_downregulated
      WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00042561:smgl-2(RNAi)_upregulated
      WBPaper00044037:eat-2_upregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00045257:bar-1(ga80)_upregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045774:clk-1_upregulated
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00053402:cco-1(RNAi)_upregulated
      WBPaper00053402:his-3(RNAi)_upregulated
      WBPaper00053771:up_at_dpy-7(e88)
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055013:spt-16(RNAi)_upregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055648:nerve-ring_expressed
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056809:smn-1(ok355)_upregulated
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060886:spr-5(by101);met-2(n4256)_upregulated
      WBPaper00061340:DVC
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061527:ckr-1-T09B9.3
      WBPaper00061995:mter-4(syb3662syb3403)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00065841:26_1
      WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00030985:Serratia_marcesens_upregulated
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00036123:Fluoranthene_regulated
      WBPaper00036286:Pattern_I
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00045673:colistin_downregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00048989:N2_allantoin_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
    Interaction: WBInteraction000301747
      WBInteraction000418232
      WBInteraction000456158
      WBInteraction000467553
  Map_info: Map: V Position: 0.956731 Error: 0.001792
    Positive: Positive_clone: Y97E10B Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00062223
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene