WormBase Tree Display for Gene: WBGene00007880

WBGene00007880 SMap: S_parent: Sequence: C33A12
  Identity: Version: 2
    Name: CGC_name: ndua-5 Person_evidence: WBPerson25803
            WBPerson545
      Sequence_name: C33A12.1
      Molecular_name: C33A12.1
        C33A12.1.1
        CE05347
      Other_name: CELE_C33A12.1 Accession_evidence: NDB BX284604
      Public_name: ndua-5
    DB_info: Database: AceView gene 4K286
        WormQTL gene WBGene00007880
        WormFlux gene WBGene00007880
        NDB locus_tag CELE_C33A12.1
        Panther gene CAEEL|WormBase=WBGene00007880|UniProtKB=Q18359
          family PTHR12653
        NCBI gene 177786
        RefSeq protein NM_069287.6
        SwissProt UniProtAcc Q18359
        TREEFAM TREEFAM_ID TF313785
        UniProt_GCRP UniProtAcc Q18359
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:48 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 12 Jan 2023 20:48:33 WBPerson51134 Name_change: CGC_name: ndua-5
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ndua
    Allele (23)
    Strain: WBStrain00002888
    RNASeq_FPKM (74)
    GO_annotation: 00061016
      00061017
      00061018
      00061019
      00061020
      00061021
      00061022
      00061023
      00061024
      00115881
    Ortholog (37)
    Structured_description: Concise_description: C33A12.1 encodes the C. elegans ortholog of the NDUFA5/B13 subunit of the mitochondrial NADH dehydrogenase (ubiquinone) complex (complex I). Paper_evidence: WBPaper00005928
          Curator_confirmed: WBPerson1843
          Date_last_updated: 07 Nov 2006 00:00:00
      Automated_description: Predicted to be involved in respiratory electron transport chain. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human NDUFA5 (NADH:ubiquinone oxidoreductase subunit A5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7688)
  Molecular_info: Corresponding_CDS: C33A12.1
    Corresponding_transcript: C33A12.1.1
    Other_sequence (61)
    Associated_feature: WBsf652070
      WBsf997432
      WBsf997433
      WBsf1017971
      WBsf1017972
      WBsf1017973
      WBsf230585
  Experimental_info: RNAi_result (15)
    Expr_pattern: Chronogram1794
      Expr5405
      Expr1029208
      Expr1033412
      Expr1145739
      Expr2001329
      Expr2019552
    Drives_construct: WBCnstr00003407
      WBCnstr00033412
    Construct_product: WBCnstr00033412
    Microarray_results (19)
    Expression_cluster: WBPaper00029359_1166
      WBPaper00029359_1197
      WBPaper00029359_1291
      WBPaper00029359_1320
      WBPaper00029359_1326
      WBPaper00029359_1345
      WBPaper00029359_1439
      WBPaper00029359_1458
      WBPaper00029359_1546
      WBPaper00029359_1549
      WBPaper00029359_1557
      WBPaper00029359_1599
      WBPaper00029359_1618
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037047:insoluble_protein
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037086:biotin_regulated
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_larva_enriched
      WBPaper00038118:aak-2(gt33)_downregulated
      WBPaper00038118:stress_downregulated_N2
      WBPaper00038289:oocyte_protein
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040965:lipid-droplet_associated_protein
      WBPaper00043951:insoluble_protein_day16_N2
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00045460:pept-1(lg601)_downregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00048910:Apoptosis-induced_mRNA-interacting_protein
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051265:F4_morc-1(tm6048)_downregulated
      WBPaper00051558:aging_regulated
      WBPaper00053289:DREAM-target
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056501:P.aeruginosa_upregulated_mitochondria-protein
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00056900:PID-3_interacting
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_protein
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00060006:nfyb-1(cu13)_downregulated_protein
      WBPaper00060014:set-2(zr2012)_upregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061377:MYRF-2_interacting
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061527:C18E9.4-T27E9.2
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00025032:cluster_190
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026629:L2_male_enriched
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00036286:Pattern_G
      WBPaper00036375:depleted_in_PVD_OLL
      WBPaper00040963:TA100_up
      WBPaper00040963:TA300_up
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
    Interaction (103)
  Map_info: Map: IV Position: 4.29053
    Positive: Positive_clone: C33A12 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00005928
    WBPaper00031194
    WBPaper00038491
    WBPaper00041771
    WBPaper00049828
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene